Species : |
Human |
Source : |
E.coli |
Tag : |
His |
Protein Length : |
1-569 aa |
Description : |
AMP-activated protein kinase (AMPK) is a heterotrimeric protein composed of a catalytic alpha subunit, a noncatalytic beta subunit, and a noncatalytic regulatory gamma subunit. Various forms of each of these subunits exist, encoded by different genes. AMPK is an important energy-sensing enzyme that monitors cellular energy status and functions by inactivating key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This gene is a member of the AMPK gamma subunit family. Mutations in this gene have been associated with Wolff-Parkinson-White syndrome, familial hypertrophic cardiomyopathy, and glycogen storage disease of the heart. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
Molecular Mass : |
62.9 kDa |
Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
Notes : |
For testing in cell culture applications, please filter before use. Note that you may experience some loss of protein during the filtration process. |
Stability : |
Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles. |
Storage : |
Store at -80 centigrade. |
Storage Buffer : |
50 mM Tris-HCl, pH 8.0, 8 M urea |
Concentration : |
> 0.05 μg/μL as determined by microplate BCA method |