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Recombinant Human PRKCD Protein, His-tagged

Cat.No. : PRKCD-653H
Product Overview : Recombinant Human PRKCD(Asn330~His672) fused with His tag at N-terminal was expressed in E. coli.
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Description : Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. The protein encoded by this gene is one of the PKC family members. Studies both in human and mice demonstrate that this kinase is involved in B cell signaling and in the regulation of growth, apoptosis, and differentiation of a variety of cell types. Alternatively spliced transcript variants encoding the same protein have been observed.
Source : E. coli
Species : Human
Tag : His
Form : PBS, pH7.4, containing 0.01% SKL, 1mM DTT, 5% Trehalose and Proclin300.
Molecular Mass : 43.4kDa
Identity : Reconstitute in PBS or others
Protein length : Asn330~His672
Endotoxin : <1.0EU per 1µg (determined by the LAL method)
Purity : > 95%
Applications : Positive Control; Immunogen; SDS-PAGE; WB.
If bio-activity of the protein is needed, please check active protein
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37 centigrade for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8 centigrade for one month. Aliquot and store at -80 centigrade for 12 months.
Reconstitution : Reconstitute in PBS or others
Gene Name : PRKCD protein kinase C, delta [ Homo sapiens ]
Official Symbol : PRKCD
Synonyms : PRKCD; protein kinase C, delta; protein kinase C delta type; protein kinase C delta VIII; tyrosine-protein kinase PRKCD; MAY1; PKCD; nPKC-delta; MGC49908;
Gene ID : 5580
mRNA Refseq : NM_006254
Protein Refseq : NP_006245
MIM : 176977
UniProt ID : Q05655

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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Q&As (5)

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Are there any side effects associated with targeting PRKCD in therapy? 10/19/2021

Like any targeted therapy, there may be side effects associated with PRKCD inhibitors, and ongoing clinical trials aim to assess the safety profile of these potential treatments.

Is PRKCD involved in the regulation of inflammation? 11/22/2019

Yes, PRKCD is implicated in the regulation of inflammation, and its modulation could be explored for the development of anti-inflammatory therapies.

Can PRKCD be a target for personalized medicine? 09/25/2019

The role of PRKCD in various diseases suggests that it could be a potential target for personalized medicine, tailoring treatments based on an individual's molecular profile.

How does PRKCD impact immune response? 11/22/2017

PRKCD has been found to influence immune response, and its modulation could potentially be harnessed to enhance the body's ability to fight off infections or respond to immunotherapies.

Can PRKCD be a potential biomarker for cancer diagnosis? 07/05/2016

Research suggests that the expression levels of PRKCD may serve as a biomarker for certain cancers, aiding in early diagnosis and prognosis.

Customer Reviews (3)

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Reviews
09/12/2021

    Their knowledgeable and responsive team has consistently demonstrated their ability to address any concerns or challenges I have encountered along the way.

    04/11/2020

      Its versatility allows for exploring its various roles and functions, shedding light on its significance in crucial biochemical pathways and cellular processes.

      06/17/2018

        Their support has been invaluable in troubleshooting and providing efficient solutions, enhancing the overall efficiency and productivity of my experiments.

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