Recombinant Human PRMT1 Protein, GST-tagged
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| Cat.No. : | PRMT1-016H |
| Product Overview : | Recombinant Human PRMT1 protein (2-371) with a N-terminal GST-tag was expressed in E. coli |
| Description : | This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5. |
| Source : | E. coli |
| Species : | Human |
| Tag : | GST |
| Molecular Mass : | 69.2 kDa |
| Protein length : | 2-371 |
| Purity : | ≥35% estimated by SDS-PAGE |
| Unit Definition : | One unit is the amount of enzyme required to transfer one methyl group to histone H4 per minute using 100 µmol histone H4 (1-21) peptide at 37 centigrade in Methyltransferase Colorimetric Assay Kit. |
| Stability : | ≥ 6 months |
| Storage : | -80 centigrade |
| Shipping : | Dry ice in continental US, may vary elsewhere. |
| Activity of PRMT1 : |
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| SDS-PAGE analysis of PRMT1 : |
Lane 1: MW Markers |
| Gene Name : | PRMT1 protein arginine methyltransferase 1 [ Homo sapiens (human) ] |
| Official Symbol : | PRMT1 |
| Synonyms : | PRMT1; protein arginine methyltransferase 1; ANM1; HCP1; IR1B4; HRMT1L2; protein arginine N-methyltransferase 1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2; heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2; histone arginine N-methyltransferase PRMT1; interferon receptor 1-bound protein 4; EC 2.1.1.319 |
| Gene ID : | 3276 |
| mRNA Refseq : | NM_001536 |
| Protein Refseq : | NP_001527 |
| MIM : | 602950 |
| UniProt ID : | Q99873 |
◆ Recombinant Protein
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| Prmt1-711R | Recombinant Rat Protein Arginine Methyltransferase 1 | +Inquiry |
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◆ Lysates
| PRMT1-500HCL | Recombinant Human PRMT1 lysate | +Inquiry |
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◆ Assay kits
| Kit-1854 | PRMT1 Homogeneous Assay Kit | +Inquiry |
| Kit-1853 | PRMT1 Chemiluminescent Assay Kit | +Inquiry |
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