Recombinant Human PRMT1 protein (2-371) with a N-terminal GST-tag was expressed in E. coli
Description :
This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
Source :
E. coli
Species :
Human
Tag :
GST
Molecular Mass :
69.2 kDa
Protein length :
2-371
Purity :
≥35% estimated by SDS-PAGE
Unit Definition :
One unit is the amount of enzyme required to transfer one methyl group to histone H4 per minute using 100 µmol histone H4 (1-21) peptide at 37 centigrade in Methyltransferase Colorimetric Assay Kit.
Stability :
≥ 6 months
Storage :
-80 centigrade
Shipping :
Dry ice in continental US, may vary elsewhere.
Activity of PRMT1 :
SDS-PAGE analysis of PRMT1 :
Lane 1: MW Markers Lane 2: PRMT1 (1 µg) Lane 3: PRMT1 (2 µg) Lane 4: PRMT1 (4 µg)
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.