Recombinant Human PRMT1 Protein, GST-tagged PRMT1-016H

Recombinant Human PRMT1 Protein, GST-tagged

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Recombinant Human PRMT1 Protein, GST-tagged

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Cat.No. : PRMT1-016H
Product Overview : Recombinant Human PRMT1 protein (2-371) with a N-terminal GST-tag was expressed in E. coli
Description : This gene encodes a member of the protein arginine N-methyltransferase (PRMT) family. Post-translational modification of target proteins by PRMTs plays an important regulatory role in many biological processes, whereby PRMTs methylate arginine residues by transferring methyl groups from S-adenosyl-L-methionine to terminal guanidino nitrogen atoms. The encoded protein is a type I PRMT and is responsible for the majority of cellular arginine methylation activity. Increased expression of this gene may play a role in many types of cancer. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene, and a pseudogene of this gene is located on the long arm of chromosome 5.
Source : E. coli
Species : Human
Tag : GST
Molecular Mass : 69.2 kDa
Protein length : 2-371
Purity : ≥35% estimated by SDS-PAGE
Unit Definition : One unit is the amount of enzyme required to transfer one methyl group to histone H4 per minute using 100 µmol histone H4 (1-21) peptide at 37 centigrade in Methyltransferase Colorimetric Assay Kit.
Stability : ≥ 6 months
Storage : -80 centigrade
Shipping : Dry ice in continental US, may vary elsewhere.
Activity of PRMT1 :

SDS-PAGE analysis of PRMT1 :

Lane 1: MW Markers
Lane 2: PRMT1 (1 µg)
Lane 3: PRMT1 (2 µg)
Lane 4: PRMT1 (4 µg)

Gene Name : PRMT1 protein arginine methyltransferase 1 [ Homo sapiens (human) ]
Official Symbol : PRMT1
Synonyms : PRMT1; protein arginine methyltransferase 1; ANM1; HCP1; IR1B4; HRMT1L2; protein arginine N-methyltransferase 1; HMT1 (hnRNP methyltransferase, S. cerevisiae)-like 2; heterogeneous nuclear ribonucleoprotein methyltransferase 1-like 2; histone arginine N-methyltransferase PRMT1; interferon receptor 1-bound protein 4; EC 2.1.1.319
Gene ID : 3276
mRNA Refseq : NM_001536
Protein Refseq : NP_001527
MIM : 602950
UniProt ID : Q99873

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