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Recombinant Human PRMT6 Protein, His-tagged
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Cat.No. : | PRMT6-044H |
Product Overview : | Recombinant N-terminal His-tagged human PRMT6 protein was expressed in Sf21 cells. |
Description : | The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity. |
Source : | Insect cell |
Species : | Human |
Tag : | His |
Molecular Mass : | 43.7 kDa |
Purity : | ≥60% |
Stability : | ≥ 2 years |
Storage : | At -80 centigrade. |
Storage Buffer : | 50 mM Tris-HCl, pH 8.0, containing 150 mM sodium chloride, and 20% glycerol |
SDS-PAGE analysis of PRMT6 : |
![]() Lane 1: MW Markers |
Gene Name : | PRMT6 protein arginine methyltransferase 6 [ Homo sapiens (human) ] |
Official Symbol : | PRMT6 |
Synonyms : | PRMT6; protein arginine methyltransferase 6; HRMT1L6; protein arginine N-methyltransferase 6; HMT1 hnRNP methyltransferase-like 6; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; histone-arginine N-methyltransferase PRMT6; EC 2.1.1.319 |
Gene ID : | 55170 |
mRNA Refseq : | NM_018137 |
Protein Refseq : | NP_060607 |
MIM : | 608274 |
UniProt ID : | Q96LA8 |
◆ Recombinant Protein
PRMT6-5044H | Recombinant Human PRMT6 Protein, GST-tagged | +Inquiry |
PRMT6-001H | Recombinant Human PRMT6 Protein, His-tagged | +Inquiry |
PRMT6-3002H | Recombinant Human PRMT6 Protein, MYC/DDK-tagged | +Inquiry |
Prmt6-5134M | Recombinant Mouse Prmt6 Protein, Myc/DDK-tagged | +Inquiry |
PRMT6-13420M | Recombinant Mouse PRMT6 Protein | +Inquiry |
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◆ Lysates
PRMT6-2458HCL | Recombinant Human PRMT6 cell lysate | +Inquiry |
|
◆ Assay kits
Kit-1861 | PRMT6 (HRMT1L6) Homogeneous Assay Kit | +Inquiry |
Kit-1860 | PRMT6 (HRMT1L6) Chemiluminescent Assay Kit | +Inquiry |
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