Recombinant Human PRMT6 Protein, His-tagged PRMT6-044H

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Recombinant Human PRMT6 Protein, His-tagged

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Cat.No. :	PRMT6-044H
Product Overview :	Recombinant N-terminal His-tagged human PRMT6 protein was expressed in Sf21 cells.
Description :	The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Source :	Insect cell
Species :	Human
Tag :	His
Molecular Mass :	43.7 kDa
Purity :	≥60%
Stability :	≥ 2 years
Storage :	At -80 centigrade.
Storage Buffer :	50 mM Tris-HCl, pH 8.0, containing 150 mM sodium chloride, and 20% glycerol
SDS-PAGE analysis of PRMT6 :	Lane 1: MW Markers Lane 2: PRMT6 (4 μg) Lane 3: PRMT6 (4 μg)

Gene Name :	PRMT6 protein arginine methyltransferase 6 [ Homo sapiens (human) ]
Official Symbol :	PRMT6
Synonyms :	PRMT6; protein arginine methyltransferase 6; HRMT1L6; protein arginine N-methyltransferase 6; HMT1 hnRNP methyltransferase-like 6; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; histone-arginine N-methyltransferase PRMT6; EC 2.1.1.319
Gene ID :	55170
mRNA Refseq :	NM_018137
Protein Refseq :	NP_060607
MIM :	608274
UniProt ID :	Q96LA8