Recombinant Human PRMT6 Protein, His-tagged


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Recombinant Human PRMT6 Protein, His-tagged

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Cat.No. : PRMT6-044H
Product Overview : Recombinant N-terminal His-tagged human PRMT6 protein was expressed in Sf21 cells.
Description : The protein encoded by this gene belongs to the arginine N-methyltransferase family, which catalyze the sequential transfer of methyl group from S-adenosyl-L-methionine to the side chain nitrogens of arginine residues within proteins, to form methylated arginine derivatives and S-adenosyl-L-homocysteine. This protein can catalyze both, the formation of omega-N monomethylarginine and asymmetrical dimethylarginine, with a strong preference for the latter. It specifically mediates the asymmetric dimethylation of Arg2 of histone H3, and the methylated form represents a specific tag for epigenetic transcriptional repression. This protein also forms a complex with, and methylates DNA polymerase beta, resulting in stimulation of polymerase activity by enhancing DNA binding and processivity.
Source : Insect cell
Species : Human
Tag : His
Molecular Mass : 43.7 kDa
Purity : ≥60%
Stability : ≥ 2 years
Storage : At -80 centigrade.
Storage Buffer : 50 mM Tris-HCl, pH 8.0, containing 150 mM sodium chloride, and 20% glycerol
SDS-PAGE analysis of PRMT6 :

Lane 1: MW Markers
Lane 2: PRMT6 (4 μg)
Lane 3: PRMT6 (4 μg)

Gene Name : PRMT6 protein arginine methyltransferase 6 [ Homo sapiens (human) ]
Official Symbol : PRMT6
Synonyms : PRMT6; protein arginine methyltransferase 6; HRMT1L6; protein arginine N-methyltransferase 6; HMT1 hnRNP methyltransferase-like 6; heterogeneous nuclear ribonucleoprotein methyltransferase-like protein 6; histone-arginine N-methyltransferase PRMT6; EC
Gene ID : 55170
mRNA Refseq : NM_018137
Protein Refseq : NP_060607
MIM : 608274
UniProt ID : Q96LA8
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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