Recombinant Human PRNP Protein, Lys23-Ser230, C-His-Avi tagged, Biotinylated
Cat.No. : | PRNP-12HB |
Product Overview : | Biotinylated recombinant Human PRNP Protein (Lys23-Ser230) with C-His-Avi tag was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
Description : | The protein encoded by this gene is a membrane glycosylphosphatidylinositol-anchored glycoprotein that tends to aggregate into rod-like structures. The encoded protein contains a highly unstable region of five tandem octapeptide repeats. This gene is found on chromosome 20, approximately 20 kbp upstream of a gene which encodes a biochemically and structurally similar protein to the one encoded by this gene. Mutations in the repeat region as well as elsewhere in this gene have been associated with Creutzfeldt-Jakob disease, fatal familial insomnia, Gerstmann-Straussler disease, Huntington disease-like 1, and kuru. An overlapping open reading frame has been found for this gene that encodes a smaller, structurally unrelated protein, AltPrp. Alternative splicing results in multiple transcript variants. |
Source : | HEK293 |
Species : | Human |
Tag : | C-His-Avi |
Protein length : | Lys23-Ser230 |
Conjugation/Label : | Biotin |
Molecular Mass : | 25 kDa |
AA Sequence : | KKRPKPGGWNTGGSRYPGQGSPGGN RYPPQGGGGWGQPHGGGWGQPHGGG WGQPHGGGWGQPHGGGWGQGGGTHS QWNKPSKPKTNMKHMAGAAAAGAVV GGLGGYMLGSAMSRPIIHFGSDYED RYYRENMHRYPNQVYYRPMDEYSNQ NNFVHDCVNITIKQHTVTTTTKGEN FTETDVKMMERVVEQMCITQYERES QAYYQRGSHHHHHHHHGLNDIFEAQ KIEWHE |
Endotoxin : | < 1 EU/μg by LAL |
Purity : | > 90% by SDS-PAGE |
Storage : | Store it under sterile conditions at -20 to -80 centigrade. It is recommended that the protein be aliquoted for optimal storage. Avoid repeated freeze-thaw cycles. |
Concentration : | 0.42 mg/mL by Bradford |
Storage Buffer : | Sterile 50mM tris, pH8.0, 300mM NaCl, 2mM DTT, 0.01% SKL, 20% Glycerol |
Gene Name : | PRNP prion protein (Kanno blood group) [ Homo sapiens (human) ] |
Official Symbol : | PRNP |
Synonyms : | PRNP; prion protein (Kanno blood group); CJD; GSS; PrP; ASCR; KURU; PRIP; PrPc; CD230; AltPrP; p27-30; PrP27-30; PrP33-35C; major prion protein; alternative prion protein; CD230 antigen; prion-related protein |
Gene ID : | 5621 |
mRNA Refseq : | NM_000311 |
Protein Refseq : | NP_000302 |
MIM : | 176640 |
UniProt ID : | P04156 |
Products Types
◆ Recombinant Protein | ||
PRP-02C | Recombinant Cervid PRNP protein, His-tagged | +Inquiry |
PRNP-742R | Recombinant Rat PRNP Protein (29-231 aa), His-tagged | +Inquiry |
PRNP-555C | Recombinant Cynomolgus Monkey PRNP Protein, His (Fc)-Avi-tagged | +Inquiry |
PRNP-118H | Recombinant Human PRNP Protein, His-tagged | +Inquiry |
PRNP-7129M | Recombinant Mouse PRNP Protein, His (Fc)-Avi-tagged | +Inquiry |
◆ Lysates | ||
PRNP-001HCL | Recombinant Human PRNP cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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