Recombinant Human PROM1 Protein, DYKDDDDK-tagged

• Cat.No.: PROM1-953H
• Product Overview: Recombinant Human prominin 1(PROM1) protein, transcript variant 1(NM_006017), with a DYKDDDDK tag, was expressed in human cells.

Specification

• Description: This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.
• Source: Human cells
• Species: Human
• Tag: DYKDDDDK
• Form: Purified protein formulated in a sterile solution of TBS buffer, pH7.334, without any preservatives.
• Molecular Mass: 97 kDa
• Endotoxin: Endotoxin level is < 0.1 ng/µg of protein (<1EU /µg)
• Purity: >90% by SDS-PAGE gel and Coomassie Blue staining
• Applications: Antigens, Western, ELISA and other in vitro binding or in vivo functional assays, and protein-protein interaction studies.

Gene Information

• Gene Name: PROM1 prominin 1 [ Homo sapiens ]
• Official Symbol: PROM1
• Synonyms: PROM1; prominin 1; macular dystrophy, retinal 2 , MCDR2, prominin (mouse) like 1 , PROML1, Stargardt disease 4 (autosomal dominant) , STGD4; prominin-1; AC133; CD133; RP41; hProminin; antigen AC133; prominin-like protein 1; hematopoietic stem cell antigen; MCDR2; STGD4; CORD12; PROML1; MSTP061
• Gene ID: 8842
• mRNA Refseq: NM_001145847
• Protein Refseq: NP_001139319
• MIM: 604365
• UniProt ID: O43490