Recombinant Human PRPS1
Cat.No. : | PRPS1-30999TH |
Product Overview : | Recombinant full length Human PRPS1, expressed in Saccharomyces cerevisiae. 318 aas. MW 35kDa. |
- Specification
- Gene Information
- Related Products
Description : | This gene encodes an enzyme that catalyzes the phosphoribosylation of ribose 5-phosphate to 5-phosphoribosyl-1-pyrophosphate, which is necessary for purine metabolism and nucleotide biosynthesis. Defects in this gene are a cause of phosphoribosylpyrophosphate synthetase superactivity, Charcot-Marie-Tooth disease X-linked recessive type 5 and Arts Syndrome. Two transcript variants encoding different isoforms have been found for this gene. |
Form : | Liquid |
Purity : | >90% by SDS-PAGE |
Storage buffer : | Preservative: NoneConstituents: 30% Glycerol, 0.5% Triton-X-100, 50mM HEPES, 30mM Glutathione, 100mM Sodium chloride, 1mM DTT, pH 7.5 |
Storage : | Store at -20°C. Stable for 12 months at -20°C |
Sequences of amino acids : | MPNIKIFSGSSHQDLSQKIADRLGL ELGKVVTKKFSNQET CVEIGESVRGEDVYIVQSGCGEIND NLMELLIMINACK IASASRVTAVIPCFPYARQDKKDKS RAPISAKLVANMLSV AGADHIITMDLHASQIQGFFDIPVD NLYAEPAVLKWIR ENISEWRNCTIVSPDAGGAKRVTSI ADRLNVDFALIHKER KKANEVDRMVLVGDVKDRVAILVDD MADTCGTICHAAD KLLSAGATRVYAILTHGIFSGPAIS RINNACFEAVVVTNTIPQEDKMKHC SKIQVIDISMILAEAIRRTHNGESV SYL FSHVPL |
Sequence Similarities : | Belongs to the ribose-phosphate pyrophosphokinase family. |
Gene Name : | PRPS1 phosphoribosyl pyrophosphate synthetase 1 [ Homo sapiens ] |
Official Symbol : | PRPS1 |
Synonyms : | PRPS1; phosphoribosyl pyrophosphate synthetase 1; deafness, X linked 2, perceptive, congenital , DFN2; ribose-phosphate pyrophosphokinase 1; CMTX5; DFNX1; PRS I; ribose phosphate diphosphokinase 1; |
Gene ID : | 5631 |
mRNA Refseq : | NM_001204402 |
Protein Refseq : | NP_001191331 |
MIM : | 311850 |
Uniprot ID : | P60891 |
Chromosome Location : | Xq21-q27 |
Pathway : | 5-Phosphoribose 1-diphosphate biosynthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; Metabolism of carbohydrates, organism-specific biosystem; Nucleotide Metabolism, organism-specific biosystem; PRPP biosynthesis, ribose 5P => |
Function : | ATP binding; kinase activity; magnesium ion binding; nucleotide binding; protein homodimerization activity; |
Products Types
◆ Recombinant Protein | ||
PRPS1-4382R | Recombinant Rat PRPS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRPS1-3444R | Recombinant Rhesus Macaque PRPS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRPS1-557C | Recombinant Cynomolgus Monkey PRPS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
PRPS1-7150M | Recombinant Mouse PRPS1 Protein, His (Fc)-Avi-tagged | +Inquiry |
Prps1-5152M | Recombinant Mouse Prps1 Protein, Myc/DDK-tagged | +Inquiry |
◆ Lysates | ||
PRPS1-2820HCL | Recombinant Human PRPS1 293 Cell Lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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