| Description : |
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain. For additional general information about the PSG gene family. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
47.9 kDa |
| AA Sequence : |
MGPLSAPPCTQRITWKGLLLTALLL NFWNLPTTAQVTIEAEPTKVSKGKD VLLLVHNLPQNLAGYIWYKGQMKDL YHYITSYVVDGQIIIYGPAYSGRET VYSNASLLIQNVTREDAGSYTLHIV KRGDGTRGETGHFTFTLYLETPKPS ISSSNLYPREDMEAVSLTCDPETPD ASYLWWMNGQSLPMTHSLQLSKNKR TLFLFGVTKYTAGPYECEIRNPVSA SRSDPVTLNLLPKLPKPYITINNLN PRENKDVLAFTCEPKSENYTYIWWL NGQSLPVSPRVKRPIENRILILPSV TRNETGPYQCEIQDRYGGIRSYPVT LNVLYGPDLPRIYPSFTYYHSGENL YLSCFADSNPPAEYSWTINGKFQLS GQKLFIPQITTKHSGLYACSVRNSA TGMESSKSMTVEVSAPSGTGHLPGL NPLTRTRPLEQKLISEEDLAANDIL DYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
