| Description : |
The human pregnancy-specific glycoproteins (PSGs) are a family of proteins that are synthesized in large amounts by placental trophoblasts and released into the maternal circulation during pregnancy. Molecular cloning and analysis of several PSG genes has indicated that the PSGs form a subgroup of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily of genes. Members of the CEA family consist of a single N domain, with structural similarity to the immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. Most PSGs have an arg-gly-asp (RGD) motif, which has been shown to function as an adhesion recognition signal for several integrins, in the N-terminal domain (summary by Teglund et al., 1994 [PubMed 7851896]). For additional general information about the PSG gene family, see PSG1 (MIM 176390). |
| Source : |
HEK293 cells |
| Tag : |
His |
| Form : |
Lyophilized from a 0.2 µM filtered solution of 20mM PB, 150mM NaCl, pH7.4 |
| Molecular Mass : |
45.2kD |
| AA Sequence : |
QVTIEAEPTKVSKGKDVLLLVHNLP QNLAGYIWYKGQMKDLYHYITSYVV DGQIIIYGPAYSGRETVYSNASLLI QNVTREDAGSYTLHIVKRGDGTRGE TGHFTFTLYLETPKPSISSSNLYPR EDMEAVSLTCDPETPDASYLWWMNG QSLPMTHSLQLSKNKRTLFLFGVTK YTAGPYECEIRNPVSASRSDPVTLN LLPKLPKPYITINNLNPRENKDVLA FTCEPKSENYTYIWWLNGQSLPVSP RVKRPIENRILILPSVTRNETGPYQ CEIQDRYGGIRSYPVTLNVLYGPDL PRIYPSFTYYHSGENLYLSCFADSN PPAEYSWTINGKFQLSGQKLFIPQI TTKHSGLYACSVRNSATGMESSKSM TVEVSAPSGTGHLPGLNPLVDHHHH HH* |
| Endotoxin : |
Endotoxin level is <0.1 ng/µg of protein (<1EU/µg). |
| Purity : |
>95% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
Always centrifuge tubes before opening. Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100 µg/ml. Dissolve the lyophilized protein in 1X PBS. Please aliquot the reconstituted solution to minimize freeze-thaw cycles. |
