Gene Name |
PSMA1 proteasome (prosome, macropain) subunit, alpha type, 1 [ Homo sapiens ] |
Official Symbol |
PSMA1 |
Synonyms |
PSMA1; proteasome (prosome, macropain) subunit, alpha type, 1; proteasome subunit alpha type-1; HC2; MGC1667; MGC14542; MGC14575; MGC14751; MGC21459; MGC22853; MGC23915; NU; PROS30; PROS-30; protein P30-33K; proteasome nu chain; macropain subunit C2; macropain subunit nu; proteasome subunit nu; 30 kDa prosomal protein; proteasome component C2; proteasome subunit, alpha-type, 1; multicatalytic endopeptidase complex subunit C2; |
Gene ID |
5682 |
mRNA Refseq |
NM_001143937 |
Protein Refseq |
NP_001137409 |
MIM |
602854 |
UniProt ID |
P25786 |
Chromosome Location |
11p15.1 |
Pathway |
APC/C-mediated degradation of cell cycle proteins, organism-specific biosystem; APC/C:Cdc20 mediated degradation of Securin, organism-specific biosystem; APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1, organism-specific biosystem; Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins, organism-specific biosystem; Activation of NF-kappaB in B Cells, organism-specific biosystem; Adaptive Immune System, organism-specific biosystem; |
Function |
RNA binding; peptidase activity; protein binding; threonine-type endopeptidase activity; |