Recombinant Human PSMC3 Protein (Asn2-Ala439), His tagged

• Cat.No.: PSMC3-3173H
• Product Overview: Recombinant human PSMC3 (Asn2-Ala439) protein fused with His tag was expressed in E. coli.

Specification

• Description: Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair. PSMC3 belongs to the heterohexameric ring of AAA (ATPases associated with diverse cellular activities) proteins that unfolds ubiquitinated target proteins that are concurrently translocated into a proteolytic chamber and degraded into peptides.
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 47.57 kDa
• Protein Length: Asn2-Ala439
• Purity: >90 % as determined by SDS-PAGE.
• Notes: For research use only.
• Storage: Use a manual defrost freezer and avoid repeated freeze thaw cycles. Store at 2 to 8 centigrade for one week. Store at -20 to -80 centigrade for twelve months from the date of receipt.
• Storage Buffer: Supplied as solution form in PBS pH 7.5 or lyophilized from PBS pH 7.5.
• Reconstitution: Reconstitute in sterile water for a stock solution.
• Shipping: In general, proteins are provided as lyophilized powder/frozen liquid. They are shipped out with dry ice/blue ice unless customers require otherwise.

Gene Information

• Gene Name: PSMC3 proteasome (prosome, macropain) 26S subunit, ATPase, 3 [ Homo sapiens (human) ]
• Official Symbol: PSMC3
• Synonyms: PSMC3; proteasome (prosome, macropain) 26S subunit, ATPase, 3; 26S protease regulatory subunit 6A; TBP 1; TBP1; TBP-1; Tat-binding protein 1; proteasome subunit P50; proteasome 26S subunit ATPase 3; 26S proteasome AAA-ATPase subunit RPT5; human immunodeficiency virus tat transactivator binding protein-1; MGC8487
• Gene ID: 5702
• mRNA Refseq: NM_002804
• Protein Refseq: NP_002795
• MIM: 186852
• UniProt ID: P17980