Recombinant Human PSMD13 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PSMD13 Protein, Myc/DDK-tagged, C13 and N15-labeled

PSMD13 Related Products

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Cat.No. : PSMD13-1172H
Product Overview : PSMD13 MS Standard C13 and N15-labeled recombinant protein (NP_002808) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. Two transcripts encoding different isoforms have been described.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 42.9 kDa
AA Sequence : MKDVPGFLQQ SQSSGPGQPA VWHRLEELYT KKLWHQLTLQ VLDFVQDPCF AQGDGLIKLY ENFISEFEHR VNPLSLVEII LHVVRQMTDP NVALTFLEKT REKVKSSDEA VILCKTAIGA LKLNIGDLQV TKETIEDVEE MLNNLPGVTS VHSRFYDLSS KYYQTIGNHA SYYKDALRFL GCVDIKDLPV SEQQERAFTL GLAGLLGEGV FNFGELLMHP VLESLRNTDR QWLIDTLYAF NSGNVERFQT LKTAWGQQPD LAANEAQLLR KIQLLCLMEM TFTRPANHRQ LTFEEIAKSA KITVNEVELL VMKALSVGLV KGSIDEVDKR VHMTWVQPRV LDLQQIKGMK DRLEFWCTDV KSMEMLVEHQ AHDILTSGPT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PSMD13 proteasome 26S subunit, non-ATPase 13 [ Homo sapiens (human) ]
Official Symbol : PSMD13
Synonyms : PSMD13; proteasome (prosome, macropain) 26S subunit, non-ATPase, 13; 26S proteasome non-ATPase regulatory subunit 13; p40.5; Rpn9; 26S proteasome subunit p40.5; 26S proteasome regulatory subunit S11; 26S proteasome regulatory subunit RPN9; 26S proteasome regulatory subunit p40.5; S11; HSPC027;
Gene ID : 5719
mRNA Refseq : NM_002817
Protein Refseq : NP_002808
MIM : 603481
UniProt ID : Q9UNM6

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