Recombinant Human PTGES protein, MYC/DDK-tagged
| Cat.No. : |
PTGES-32H |
| Product Overview : |
Recombinant Human PTGES fused with MYC/DDK tag at C-terminal was expressed in HEK293. |
- Specification
- Gene Information
- Related Products
| Description : |
The protein encoded by this gene is a glutathione-dependent prostaglandin E synthase. The expression of this gene has been shown to be induced by proinflammatory cytokine interleukin 1 beta (IL1B). Its expression can also be induced by tumor suppressor protein TP53, and may be involved in TP53 induced apoptosis. Knockout studies in mice suggest that this gene may contribute to the pathogenesis of collagen-induced arthritis and mediate acute pain during inflammatory responses. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
MYC/DDK |
| Form : |
25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol. |
| Molecular Mass : |
16.9 kDa |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Concentration : |
>50 ug/mL as determined by microplate BCA method |
| Gene Name : |
PTGES prostaglandin E synthase [ Homo sapiens ] |
| Official Symbol : |
PTGES |
| Synonyms : |
PTGES; prostaglandin E synthase; MGST1L1; glutathione S transferase 1 like 1; MGST IV; MGST1 L1; MGST1 like 1; microsomal glutathione S transferase 1 like 1; microsomal prostaglandin E synthase 1; p53 induced gene 12; PIG12; TP53I12; tumor protein p53 inducible protein 12; MGST1-like 1; p53-induced gene 12 protein; p53-induced apoptosis protein 12; glutathione S-transferase 1-like 1; microsomal prostaglandin E synthase-1; microsomal glutathione S-transferase 1-like 1; PGES; MPGES; PP102; PP1294; MGST-IV; mPGES-1; MGST1-L1; MGC10317; |
| Gene ID : |
9536 |
| mRNA Refseq : |
NM_004878 |
| Protein Refseq : |
NP_004869 |
| MIM : |
605172 |
| UniProt ID : |
O14684 |
| Chromosome Location : |
9q34.3 |
| Pathway : |
Arachidonic acid metabolism, organism-specific biosystem; Arachidonic acid metabolism, conserved biosystem; Eicosanoid Synthesis, organism-specific biosystem; Metabolic pathways, organism-specific biosystem; |
| Function : |
glutathione binding; isomerase activity; prostaglandin-E synthase activity; |
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
