Recombinant Human PTGS1 Protein, His-tagged PTGS1-012H

Recombinant Human PTGS1 Protein, His-tagged

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Recombinant Human PTGS1 Protein, His-tagged

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Cat.No. : PTGS1-012H
Product Overview : Recombinant Human PTGS1 protein (24-599) with a N-terminal His-tag was expressed in baculovirus system
Description : This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. Based on its ability to function as both a cyclooxygenase and as a peroxidase, the encoded protein has been identified as a moonlighting protein. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants.
Source : Insect Cells
Species : Human
Tag : His
Molecular Mass : 70 kDa
Protein length : 24-599
Purity : ≥85% estimated by SDS-PAGE
Unit Definition : One unit is defined as the amount of enzyme required to consume 1 nmol of oxygen per minute at 37 centigrade in 100 mM Tris, pH 8.0, containing 100 µM arachidonate, 5 mM EDTA, 2 mM phenol, and 1 µM hematin.
Stability : ≥ 1 year
Storage : -80 centigrade
Storage Buffer : 80 mM Tris, pH 8.0, with 0.01% polysorbate 20, 300 µM DDC, and 10% glycerol
Shipping : Dry ice in continental US, may vary elsewhere.
SDS-PAGE Analysis of PTGS1 :

Lane 1: MW Markers
Lane 2: COX-1 (2 µg)
Lane 3: COX-1 (4 µg)

Gene Name : PTGS1 prostaglandin-endoperoxide synthase 1 [ Homo sapiens (human) ]
Official Symbol : PTGS1
Synonyms : PTGS1; prostaglandin-endoperoxide synthase 1; COX1; COX3; PHS1; PCOX1; PES-1; PGHS1; PTGHS; PGG/HS; PGHS-1; prostaglandin G/H synthase 1; PGH synthase 1; cyclooxygenase-1; prostaglandin H2 synthase 1; prostaglandin-endoperoxide synthase 1 (prostaglandin G/H synthase and cyclooxygenase); EC 1.14.99.1
Gene ID : 5742
mRNA Refseq : NM_000962
Protein Refseq : NP_000953
MIM : 176805
UniProt ID : P23219

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