Recombinant Human PTK2 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : PTK2-4856H
Product Overview : PTK2 MS Standard C13 and N15-labeled recombinant protein (NP_722560) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
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Description : This gene encodes a cytoplasmic protein tyrosine kinase which is found concentrated in the focal adhesions that form between cells growing in the presence of extracellular matrix constituents. The encoded protein is a member of the FAK subfamily of protein tyrosine kinases but lacks significant sequence similarity to kinases from other subfamilies. Activation of this gene may be an important early step in cell growth and intracellular signal transduction pathways triggered in response to certain neural peptides or to cell interactions with the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 119.1 kDa
AA Sequence : MAAAYLDPNLNHTPNSSTKTHLGTG MERSPGAMERVLKVFHYFESNSEPT TWASIIRHGDATDVRGIIQKIVDSH KVKHVACYGFRLSHLRSEEVHWLHV DMGVSSVREKYELAHPPEEWKYELR IRYLPKGFLNQFTEDKPTLNFFYQQ VKSDYMLEIADQVDQEIALKLGCLE IRRSYWEMRGNALEKKSNYEVLEKD VGLKRFFPKSLLDSVKAKTLRKLIQ QTFRQFANLNREESILKFFEILSPV YRFDKECFKCALGSSWIISVELAIG PEEGISYLTDKGCNPTHLADFTQVQ TIQYSNSEDKDRKGMLQLKIAGAPE PLTVTAPSLTIAENMADLIDGYCRL VNGTSQSFIIRPQKEGERALPSIPK LANSEKQGMRTHAVSVSETDDYAEI IDEEDTYTMPSTRDYEIQRERIELG RCIGEGQFGDVHQGIYMSPENPALA VAIKTCKNCTSDSVREKFLQEALTM RQFDHPHIVKLIGVITENPVWIIME LCTLGELRSFLQVRKYSLDLASLIL YAYQLSTALAYLESKRFVHRDIAAR NVLVSSNDCVKLGDFGLSRYMEDST YYKASKGKLPIKWMAPESINFRRFT SASDVWMFGVCMWEILMHGVKPFQG VKNNDVIGRIENGERLPMPPNCPPT LYSLMTKCWAYDPSRRPRFTELKAQ LSTILEEEKAQQEERMRMESRRQAT VSWDSGGSDEAPPKPSRPGYPSPRS SEGFYPSPQHMVQTNHYQVSGYPGS HGITAMAGSIYPGQASLLDQTDSWN HRPQEIAMWQPNVEDSTVLDLRGIG QVLPTHLMEERLIRQQQEMEEDQRW LEKEERFLKPDVRLSRGSIDREDGS LQGPIGNQHIYQPVGKPDPAAPPKK PPRPGAPGHLGSLASLSSPADSYNE GVKPWRLQPQEISPPPTANLDRSND KVYENVTGLVKAVIEMSSKIQPAPP EEYVPMVKEVGLALRTLLATVDETI PLLPASTHREIEMAQKLLNSDLGEL INKMKLAQQYVMTSLQQEYKKQMLT AAHALAVDAKNLLDVIDQARLKMLG QTRPHTRTRPLEQKLISEEDLAAND ILDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE:
Gene Name : PTK2 PTK2 protein tyrosine kinase 2 [ Homo sapiens (human) ]
Official Symbol : PTK2
Synonyms : PTK2; PTK2 protein tyrosine kinase 2; focal adhesion kinase 1; FADK; FAK; FAK1; PPP1R71; protein phosphatase 1; regulatory subunit 71; FADK 1; FAK-related non-kinase polypeptide; focal adhesion kinase-related nonkinase; protein phosphatase 1 regulatory subunit 71; protein phosphatase 1, regulatory subunit 71; FRNK; p125FAK; pp125FAK;
Gene ID : 5747
mRNA Refseq : NM_153831
Protein Refseq : NP_722560
MIM : 600758
UniProt ID : Q05397

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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