Recombinant Human PTK2B Protein Tyrosine Kinase 2 Beta, GST-tagged

• Cat.No.: PTK2B-1903H
• Product Overview: Recombinant humanfull length PTK2B with N-terminal GST tag.

Specification

• Species: Human
• Source: Insect Cells
• Tag: GST
• Description: PTK2B is a cytoplasmic tyrosine kinaseinvolved in calcium-induced regulation of ion channels and activation of themap kinase signaling pathway. No special measures were taken to activate thiskinase.
• Form: Liquid in 50 mMTris, pH 7.85 + 150 mM NaCl + 0.5 mM EDTA + 0.02% Triton X-100 + 2 mM DTT +50% glycerol.
• Molecular Weight: 145.1 kDa
• Storage: Stablefor 6 months in working aliquots at -80°C. Avoid repeated freeze-thaw cycles.
• OfficialSymbol: PTK2B
• Full Length: Full L.

Gene Information

• Gene Name: PTK2B PTK2B protein tyrosinekinase 2 beta [ Homo sapiens ]
• Synonyms: PTK2B; PTK2B protein tyrosinekinase 2 beta; PTK2B protein tyrosine kinase 2 beta; CAK beta;calcium-dependent tyrosine kinase; cell adhesion kinase beta; focal adhesionkinase 2; proline-rich tyrosine kinase 2; protein kinase B; protein tyrosinekinase 2 beta; related adhesion focal tyrosine kinase; EC 2.7.10.2
• Gene ID: 2185
• mRNA Refseq: NM_004103
• Protein Refseq: NP_004094
• MIM: 601212
• UniProt ID: Q14289
• Chromosome Location: 8p21.1
• Pathway: Calcium signaling pathway;Chemokine signaling pathway; GnRH signaling pathway; Leukocytetransendothelial migration; Natural killer cell mediated cytotoxicity
• Function: 3-phosphoinositide-dependentprotein kinase binding; ATP binding; non-membrane spanning protein tyrosinekinase activity; nucleotide binding; protein complex binding; signaltransducer activity; transferase activity