Recombinant Human PTK6 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: PTK6-2801H
• Product Overview: PTK6 MS Standard C13 and N15-labeled recombinant protein (NP_005966) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: The protein encoded by this gene is a cytoplasmic nonreceptor protein kinase which may function as an intracellular signal transducer in epithelial tissues. Overexpression of this gene in mammary epithelial cells leads to sensitization of the cells to epidermal growth factor and results in a partially transformed phenotype. Expression of this gene has been detected at low levels in some breast tumors but not in normal breast tissue. The encoded protein has been shown to undergo autophosphorylation. Alternative splicing results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 51.7 kDa
• AA Sequence: MVSRDQAHLGPKYVGLWDFKSRTDE ELSFRAGDVFHVARKEEQWWWATLL DEAGGAVAQGYVPHNYLAERETVES EPWFFGCISRSEAVRRLQAEGNATG AFLIRVSEKPSADYVLSVRDTQAVR HYKIWRRAGGRLHLNEAVSFLSLPE LVNYHRAQSLSHGLRLAAPCRKHEP EPLPHWDDWERPREEFTLCRKLGSG YFGEVFEGLWKDRVQVAIKVISRDN LLHQQMLQSEIQAMKKLRHKHILAL YAVVSVGDPVYIITELMAKGSLLEL LRDSDEKVLPVSELLDIAWQVAEGM CYLESQNYIHRDLAARNILVGENTL CKVGDFGLARLIKEDVYLSHDHNIP YKWTAPEALSRGHYSTKSDVWSFGI LLHEMFSRGQVPYPGMSNHEAFLRV DAGYRMPCPLECPPSVHKLMLTCWC RDPEQRPCFKALRERLSSFTSYENP TTRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: PTK6 PTK6 protein tyrosine kinase 6 [ Homo sapiens (human) ]
• Official Symbol: PTK6
• Synonyms: PTK6; PTK6 protein tyrosine kinase 6; protein-tyrosine kinase 6; BRK; breast tumor kinase; protein-tyrosine kinase BRK; tyrosine-protein kinase BRK; FLJ42088
• Gene ID: 5753
• mRNA Refseq: NM_005975
• Protein Refseq: NP_005966
• MIM: 602004
• UniProt ID: Q13882