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Recombinant Human PTPN14 protein, His & GST-tagged

Cat.No. : PTPN14-1676H
Product Overview : Recombinant Human PTPN14 aa. (Met1~Glu189 (Accession # Q15678)) fused with N-terminal His & GST tag was produced in E. coli cells.
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  • Gene Information
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Description : The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an N-terminal noncatalytic domain similar to that of band 4.1 superfamily cytoskeleton-associated proteins, which suggested the membrane or cytoskeleton localization of this protein. It appears to regulate lymphatic development in mammals, and a loss of function mutation has been found in a kindred with a lymphedema-choanal atresia.
Source : E. coli
Species : Human
Tag : His & GST
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 52.3kDa
Protein length : Met1~Glu189 (Accession # Q15678)
Endotoxin : <1.0EU per 1ug (determined by the LAL method)
Purity : >95%
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in 20mM Tris, 150mM NaCl, pH8.0, containing 1mM EDTA, 1mM DTT, 0.01% sarcosyl, 5% trehalose, and preservative.
Reconstitution : Reconstitute in sterile ddH2O.
Isoelectric Point : 5.8
Gene Name : PTPN14 protein tyrosine phosphatase, non-receptor type 14 [ Homo sapiens (human) ]
Official Symbol : PTPN14
Synonyms : PTPN14; protein tyrosine phosphatase, non-receptor type 14; PEZ; PTP36; tyrosine-protein phosphatase non-receptor type 14; cytoskeletal-associated protein tyrosine phosphatase; protein-tyrosine phosphatase pez
Gene ID : 5784
mRNA Refseq : NM_005401.4
Protein Refseq : NP_005392.2
UniProt ID : Q15678

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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