Recombinant Human PTPN7 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PTPN7 Protein, Myc/DDK-tagged, C13 and N15-labeled

PTPN7 Related Products

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Cat.No. : PTPN7-4695H
Product Overview : PTPN7 MS Standard C13 and N15-labeled recombinant protein (NP_542155) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This gene is preferentially expressed in a variety of hematopoietic cells, and is an early response gene in lymphokine stimulated cells. The non-catalytic N-terminus of this PTP can interact with MAP kinases and suppress the MAP kinase activities. This PTP was shown to be involved in the regulation of T cell antigen receptor (TCR) signaling, which was thought to function through dephosphorylating the molecules related to MAP kinase pathway. Multiple alternatively spliced transcript variants have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 45 kDa
AA Sequence : MGASFWPIRQ AREQQRRALS FRQTSWLSEP PLGPAPHLSM VQAHGGRSRA QPLTLSLGAA MTQPPPEKTP AKKHVRLQER RGSNVALMLD VRSLGAVEPI CSVNTPREVT LHFLRTAGHP LTRWALQRQP PSPKQLEEEF LKIPSNFVSP EDLDIPGHAS KDRYKTILPN PQSRVCLGRA QSQEDGDYIN ANYIRGYDGK EKVYIATQGP MPNTVSDFWE MVWQEEVSLI VMLTQLREGK EKCVHYWPTE EETYGPFQIR IQDMKECPEY TVRQLTIQYQ EERRSVKHIL FSAWPDHQTP ESAGPLLRLV AEVEESPETA AHPGPIVVHC SAGIGRTGCF IATRIGCQQL KARGEVDILG IVCQLRLDRG GMIQTAEQYQ FLHHTLALYA GQLPEEPSPT RTRPLEQKLI SEEDLAANDI LDYKDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PTPN7 protein tyrosine phosphatase non-receptor type 7 [ Homo sapiens (human) ]
Official Symbol : PTPN7
Synonyms : PTPN7; protein tyrosine phosphatase, non-receptor type 7; tyrosine-protein phosphatase non-receptor type 7; HEPTP; LC PTP; dual specificity phosphatase 1; protein-tyrosine phosphatase LC-PTP; hematopoietic protein-tyrosine phosphatase; protein-tyrosine phosphatase, nonreceptor-type, stress induced; LPTP; PTPNI; BPTP-4; LC-PTP; FLJ18703;
Gene ID : 5778
mRNA Refseq : NM_080588
Protein Refseq : NP_542155
MIM : 176889
UniProt ID : P35236

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