Recombinant Human PTPRK protein, His & T7-tagged

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Recombinant Human PTPRK protein, His & T7-tagged

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Cat.No. : PTPRK-1432H
Product Overview : Recombinant Human PTPRK aa. (Thr1185~Ser1440 (Accession # Q15262)) fused with N-terminal His & T7 tag was produced in E. coli cells.
Description : The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains a meprin-A5 antigen-PTP mu (MAM) domain, an Ig-like domain and four fibronectin type III-like repeats. This PTP was shown to mediate homophilic intercellular interaction, possibly through the interaction with beta- and gamma-catenin at adherens junctions. Expression of this gene was found to be stimulated by TGF-beta 1, which may be important for the inhibition of keratinocyte proliferation.
Source : E. coli
Species : Human
Tag : His & T7
Form : Freeze-dried powder
Molecular Mass : Predicted Molecular Mass: 33.3kDa.
Protein length : Thr1185~Ser1440 (Accession # Q15262)
Endotoxin : <1.0EU per 1µg (determined by the LAL method).
Purity : >95%
Characteristic : The isoelectric point is 6.
Applications : SDS-PAGE; WB; ELISA; IP.
Stability : The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
Storage : Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
Storage buffer : Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
Reconstitution : Reconstitute in sterile PBS, pH7.2-pH7.4.
SDS-PAGE :

Gene Name : PTPRK protein tyrosine phosphatase, receptor type K [ Homo sapiens (human) ]
Official Symbol : PTPRK
Synonyms : R-PTP-kappa; dJ480J14.2.1 (protein tyrosine phosphatase, receptor type, K (R-PTP-KAPPA, protein tyrosine phosphatase kappa ,; protein tyrosine phosphatase kappa; protein-tyrosine phosphatase kappa; protein-tyrosine phosphatase, receptor type, kappa; receptor-type tyrosine-protein phosphatase kappa
Gene ID : 5796
mRNA Refseq : NM_001135648.2
Protein Refseq : NP_001129120.1
UniProt ID : Q15262
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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