Recombinant Human PTPRM, GST-tagged

• Cat.No.: PTPRM-2384H
• Product Overview: Recombinant Human PTPRM(aa 839-1100) is fused at the N-terminus to a GST-tag. It is expressed inE. coli.

Specification

• Species: Human
• Source: E.coli
• Tag: GST
• Protein Length: 839-1100 a.a.
• Description: PTPµ, an Ig superfamily receptor protein tyrosine phosphatase, is involved in the control of cell-cell adhesion and the cadherin-catenin complex. It has also been shown to bind and recruit RACK1 to the plasma membrane.
• Application: Study of enzyme kinetics and regulation, dephosphorylation of target substrates, and inhibitor screening.
• Storage: -20°C.

Gene Information

• Gene Name: PTPRM protein tyrosine phosphatase, receptor type, M [ Homo sapiens ]
• Synonyms: PTPRM; protein tyrosine phosphatase, receptor type, M; RPTPM; RPTPU; PTPRL1; hR-PTPu; R-PTP-MU; MGC166994; receptor-type tyrosine-protein phosphatase mu; protein tyrosine phosphatase mu; protein tyrosine phosphatase, receptor type, mu polypeptide; EC 3.1.3.48
• Gene ID: 5797
• mRNA Refseq: NM_001105244
• Protein Refseq: NP_001098714
• MIM: 176888
• UniProt ID: P28827
• Chromosome Location: 18p11
• Pathway: Adherens junction; Cell adhesion molecules (CAMs)
• Function: cadherin binding; hydrolase activity; protein binding; protein tyrosine phosphatase activity; transmembrane receptor protein tyrosine phosphatase activity