Recombinant Human PTPRN2 Protein, MYC/DDK-tagged

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Recombinant Human PTPRN2 Protein, MYC/DDK-tagged

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Cat.No. : PTPRN2-3161H
Product Overview : Recombinant Human PTPRN2 protein, fused to MYC/DDK-tagged at C-terminus, was expressed in HEK293.
Description : This gene encodes a protein with sequence similarity to receptor-like protein tyrosine phosphatases. However, tyrosine phosphatase activity has not been experimentally validated for this protein. Studies of the rat ortholog suggest that the encoded protein may instead function as a phosphatidylinositol phosphatase with the ability to dephosphorylate phosphatidylinositol 3-phosphate and phosphatidylinositol 4,5-diphosphate, and this function may be involved in the regulation of insulin secretion. This protein has been identified as an autoantigen in insulin-dependent diabetes mellitus. Alternative splicing results in multiple transcript variants.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 109.4 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : PTPRN2 protein tyrosine phosphatase, receptor type, N polypeptide 2 [ Homo sapiens ]
Official Symbol : PTPRN2
Synonyms : IA-2beta; IAR; ICAAR; PTPRP; R-PTP-N2
Gene ID : 5799
mRNA Refseq : NM_002847
Protein Refseq : NP_002838
MIM : 601698
UniProt ID : Q92932

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