Recombinant Human PTPRO Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human PTPRO Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : PTPRO-6718H
Product Overview : PTPRO MS Standard C13 and N15-labeled recombinant protein (NP_109596) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This gene encodes a member of the R3 subtype family of receptor-type protein tyrosine phosphatases. These proteins are localized to the apical surface of polarized cells and may have tissue-specific functions through activation of Src family kinases. This gene contains two distinct promoters, and alternatively spliced transcript variants encoding multiple isoforms have been observed. The encoded proteins may have multiple isoform-specific and tissue-specific functions, including the regulation of osteoclast production and activity, inhibition of cell proliferation and facilitation of apoptosis. This gene is a candidate tumor suppressor, and decreased expression of this gene has been observed in several types of cancer.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 47.2 kDa
AA Sequence : Tag(s)MVTE MNPNVVVISV LAILSTLLIG LLLVTLIILR KKHLQMAREC GAGTFVNFAS LERDGKLPYN WRRSIFAFLT LLPSCLWTDY LLAFYINPWS KNGLKKRKLT NPVQLDDFDA YIKDMAKDSD YKFSLQFEEL KLIGLDIPHF AADLPLNRCK NRYTNILPYD FSRVRLVSMN EEEGADYINA NYIPGYNSPQ EYIATQGPLP ETRNDFWKMV LQQKSQIIVM LTQCNEKRRV KCDHYWPFTE EPIAYGDITV EMISEEEQDD WACRHFRINY ADEMQDVMHF NYTAWPDHGV PTANAAESIL QFVHMVRQQA TKSKGPMIIH CSAGVGRTGT FIALDRLLQH IRDHEFVDIL GLVSEMRSYR MSMVQTEEQY IFIHQCVQLM WMKKKQQFCI SDVIYENVSK STRTRPLEQK LISEEDLAAN DILDYKDDDD KV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : PTPRO protein tyrosine phosphatase receptor type O [ Homo sapiens (human) ]
Official Symbol : PTPRO
Synonyms : PTPRO; protein tyrosine phosphatase, receptor type, O; receptor-type tyrosine-protein phosphatase O; GLEPP1; NPHS6; osteoclastic transmembrane protein tyrosine phosphatase; PTP oc; PTP U2; PTPU2; PTP phi; PTPase U2; phosphotyrosine phosphatase U2; glomerular epithelial protein 1; protein tyrosine phosphatase PTP-U2; osteoclastic transmembrane protein-tyrosine phosphatase; PTP-OC; PTP-U2; PTPROT; R-PTP-O;
Gene ID : 5800
mRNA Refseq : NM_030671
Protein Refseq : NP_109596
MIM : 600579
UniProt ID : Q16827

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