Recombinant Human PXN Protein, His-tagged

• Cat.No.: PXN-030H
• Product Overview: Purified recombinant protein of Human paxillin (PXN), transcript variant 3, full length, with N-terminal HIS tag, was expressed in E. coli.

Specification

• Description: This gene encodes a cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion). Alternatively spliced transcript variants encoding different isoforms have been described for this gene. These isoforms exhibit different expression pattern, and have different biochemical, as well as physiological properties (PMID:9054445). [provided by RefSeq, Aug 2011].
• Source: E. coli
• Species: Human
• Tag: His
• Molecular Mass: 46.4 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Concentration: >50 µg/mL as determined by microplate BCA method
• Storage Buffer: 25mM Tris, pH 8.0, 150mM NaCl, 10% glycerol, 1% Sarkosyl.

Gene Information

• Gene Name: PXN paxillin [ Homo sapiens ]
• Official Symbol: PXN
• Synonyms: PXN; paxillin; FLJ16691
• Gene ID: 5829
• mRNA Refseq: NM_001080855
• Protein Refseq: NP_001074324
• MIM: 602505
• UniProt ID: P49023