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Recombinant Human RAPGEF6 Protein, Myc/DDK-tagged, C13 and N15-labeled

Cat.No. : RAPGEF6-5811H
Product Overview : RAPGEF6 MS Standard C13 and N15-labeled recombinant protein (NP_057424) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
  • Specification
  • Gene Information
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Description : RAPGEF6 (Rap Guanine Nucleotide Exchange Factor 6) is a Protein Coding gene. Diseases associated with RAPGEF6 include Schizoid Personality Disorder and Band Heterotopia. Among its related pathways are Ras signaling pathway and Tight junction. Gene Ontology (GO) annotations related to this gene include guanyl-nucleotide exchange factor activity and GTP-dependent protein binding. An important paralog of this gene is ENSG00000273217.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 179.2 kDa
AA Sequence : MNSPVDPGARQALRKKPPERTPEDL NTIYSYLHGMEILSNLREHQLRLMS ARARYERYSGNQVLFCSETIARCWY ILLSGSVLVKGSMVLPPCSFGKQFG GKRGCDCLVLEPSEMIVVENAKDNE DSILQREIPARQSRRRFRKINYKGE RQTITDDVEVNSYLSLPADLTKMHL TENPHPQVTHVSSSQSGCSIASDSG SSSLSDIYQATESEVGDVDLTRLPE GPVDSEDDEEEDEEIDRTDPLQGRD LVRECLEKEPADKTDDDIEQLLEFM HQLPAFANMTMSVRRELCSVMIFEV VEQAGAIILEDGQELDSWYVILNGT VEISHPDGKVENLFMGNSFGITPTL DKQYMHGIVRTKVDDCQFVCIAQQD YWRILNHVEKNTHKVEEEGEIVMVH EHRELDRSGTRKGHIVIKATPERLI MHLIEEHSIVDPTYIEDFLLTYRTF LESPLDVGIKLLEWFKIDSLRDKVT RIVLLWVNNHFNDFEGDPAMTRFLE EFEKNLEDTKMNGHLRLLNIACAAK AKWRQVVLQKASRESPLQFSLNGGS EKGFGIFVEGVEPGSKAADSGLKRG DQIMEVNGQNFENITFMKAVEILRN NTHLALTVKTNIFVFKELLFRTEQE KSGVPHIPKIAEKKSNRHSIQHVPG DIEQTSQEKGSKKVKANTVSGGRNK IRKILDKTRFSILPPKLFSDGGLSQ SQDDSIVGTRHCRHSLAIMPIPGTL SSSSPDLLQPTTSMLDFSNPSDIPD QVIRVFKVDQQSCYIIISKDTTAKE VVFHAVHEFGLTGASDTYSLCEVSV TPEGVIKQRRLPDQFSKLADRIQLN GRYYLKNNMETETLCSDEDAQELVK ESQLSMLQLSTIEVATQLSMRDFDL FRNIEPTEYIDDLFKLNSKTGNTHL KRFEDIVNQETFWVASEILTEANQL KRMKIIKHFIKIALHCRECKNFNSM FAIISGLNLASVARLRGTWEKLPSK YEKHLQDLQDIFDPSRNMAKYRNIL SSQSMQPPIIPLFPVVKKDMTFLHE GNDSKVDGLVNFEKLRMISKEIRQV VRMTSANMDPAMMFRQRSLSQGSTN SNMLDVQGGAHKKRARRSSLLNAKK LYEDAQMARKVKQYLSSLDVETDEE KFQMMSLQWEPAYGTLTKNLSEKRS AKSSEMSPVPMRSAGQTTKAHLHQP HRVSQVLQVPAVNLHPIRKKGQTKD PALNTSLPQKVLGTTEEISGKKHTE DTISVASSLHSSPPASPQGSPHKGY TLIPSAKSDNLSDSSHSEISSRSSI VSNCSVDSMSAALQDERCSSQALAV PESTGALEKTEHASGIGDHSQHGPG WTLLKPSLIKCLAVSSSVSNEEISQ EHIIIEAADSGRGSWTSCSSSSHDN FQSLPNPKSWDFLNSYRHTHLDDPI AEVEPTDSEPYSCSKSCSRTCGQCK GSLERKSWTSSSSLSDTYEPNYGTV KQRVLESTPAESSEGLDPKDATDPV YKTVTSSTEKGLIVYCVTSPKKDDR YREPPPTPPGYLGISLADLKEGPHT HLKPPDYSVAVQRSKMMHNSLSRLP PASLSSNLVACVPSKIVTQPQRHNL QPFHPKLGDVTDADSEADENEQVSA VTRTRPLEQKLISEEDLAANDILDY KDDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
Gene Name : RAPGEF6 Rap guanine nucleotide exchange factor 6 [ Homo sapiens (human) ]
Official Symbol : RAPGEF6
Synonyms : RAPGEF6; Rap guanine nucleotide exchange factor (GEF) 6; PDZ domain containing guanine nucleotide exchange factor (GEF) 2, PDZGEF2; rap guanine nucleotide exchange factor 6; PDZ GEF2; RA GEF 2; PDZ domain-containing guanine nucleotide exchange factor 2; PDZ domain-containing guanine nucleotide exchange factor I; PDZ domain containing guanine nucleotide exchange factor (GEF) 2; RAGEF2; PDZGEF2; KIA001LB; PDZ-GEF2; RA-GEF-2; DKFZp667N084; DKFZp686I15116;
Gene ID : 51735
mRNA Refseq : NM_016340
Protein Refseq : NP_057424
MIM : 610499
UniProt ID : Q8TEU7

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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