Recombinant Human RBBP7 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Recombinant Human RBBP7 Protein, Myc/DDK-tagged, C13 and N15-labeled

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Cat.No. : RBBP7-5864H
Product Overview : RBBP7 MS Standard C13 and N15-labeled recombinant protein (NP_002884) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.
Description : This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Source : HEK293
Species : Human
Tag : Myc/DDK
Molecular Mass : 47.8 kDa
AA Sequence : MASKEMFEDT VEERVINEEY KIWKKNTPFL YDLVMTHALQ WPSLTVQWLP EVTKPEGKDY ALHWLVLGTH TSDEQNHLVV ARVHIPNDDA QFDASHCDSD KGEFGGFGSV TGKIECEIKI NHEGEVNRAR YMPQNPHIIA TKTPSSDVLV FDYTKHPAKP DPSGECNPDL RLRGHQKEGY GLSWNSNLSG HLLSASDDHT VCLWDINAGP KEGKIVDAKA IFTGHSAVVE DVAWHLLHES LFGSVADDQK LMIWDTRSNT TSKPSHLVDA HTAEVNCLSF NPYSEFILAT GSADKTVALW DLRNLKLKLH TFESHKDEIF QVHWSPHNET ILASSGTDRR LNVWDLSKIG EEQSAEDAED GPPELLFIHG GHTAKISDFS WNPNEPWVIC SVSEDNIMQI WQMAENIYND EESDVTTSEL EGQGSTRTRP LEQKLISEED LAANDILDYK DDDDKV
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Stability : Stable for 3 months from receipt of products under proper storage and handling conditions.
Storage : Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
Concentration : 50 μg/mL as determined by BCA
Storage Buffer : 100 mM glycine, 25 mM Tris-HCl, pH 7.3.
SDS-PAGE :

Gene Name : RBBP7 retinoblastoma binding protein 7 [ Homo sapiens (human) ]
Official Symbol : RBBP7
Synonyms : RBBP7; retinoblastoma binding protein 7; histone-binding protein RBBP7; G1/S transition control protein binding protein RbAp46; histone acetyltransferase type B subunit 2; RbAp46; retinoblastoma binding protein p46; retinoblastoma binding protein RbAp46; RBBP-7; retinoblastoma-binding protein 7; retinoblastoma-binding protein p46; retinoblastoma-binding protein RbAp46; nucleosome-remodeling factor subunit RBAP46; G1/S transition control protein-binding protein RbAp46; MGC138867; MGC138868;
Gene ID : 5931
mRNA Refseq : NM_002893
Protein Refseq : NP_002884
MIM : 300825
UniProt ID : Q16576

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