||Recombinant Human RBFOX2(aa 1-380) fused with His tag was expressed in E. coli.
||RBFOX2 / RBM9 is one of several human genes similar to the C. elegans gene Fox-1. This gene encodes an RNA binding protein that is thought to be a key regulator of alternative exon splicing in the nervous system and other cell types. The protein binds to a conserved UGCAUG element found downstream of many alternatively spliced exons and promotes inclusion of the alternative exon in mature transcripts.
||20 mM Tris, pH 8.0, 500 mM NaCl, 50% glycerol
||MEKKKMVTQG NQEPTTTPDA MVQPFTTIPF PPPPQNGIPTEYGVPHTQDY AGQTGEHNLT LYGSTQAHGE QSSNSPSTQNGSLTTEGGAQ TDGQQSQTQS SENSESKSTP KRLHVSNIPFRFRDPDLRQM FGQFGKILDV EIIFNERGSK GFGFVTFENSADADRAREKL HGTVVEGRKI EVNNATARVM TNKKMVTPYANGWKLSPVVG AVYGPELYAA SSFQADVSLG NDAAVPLSGRGGINTYIPLI SLPLVPGFPY PTAATTAAAF RGAHLRGRGRTVYGAVRAVP PTAIPAYPGV VYQDGFYGAD LYGGYAAYRYAQPATATAAT AAAAAAAAYS DGYGRVYTAD PYHALAPAASYGVGAVASLY RGGYSRFAPY
||Long term: -80 centigrade; Short term: -20 centigrade. Avoid freeze-thaw cycles.