Recombinant Human REC8 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: REC8-2887H
• Product Overview: REC8 MS Standard C13 and N15-labeled recombinant protein (NP_005123) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 62.6 kDa
• AA Sequence: MFYYPNVLQRHTGCFATIWLAATRG SRLVKREYLRVNVVKTCEEILNYVL VRVQPPQPGLPRPRFSLYLSAQLQI GVIRVYSQQCQYLVEDIQHILERLH RAQLQIRIDMETELPSLLLPNHLAM METLEDAPDPFFGMMSVDPRLPSPF DIPQIRHLLEAAIPERVEEIPPEVP TEPREPERIPVTVLPPEAITILEAE PIRMLEIEGERELPEVSRRELDLLI AEEEEAILLEIPRLPPPAPAEVEGI GEALGPEELRLTGWEPGALLMEVTP PEELRLPAPPSPERRPPVPPPPRRR RRRRLLFWDKETQISPEKFQEQLQT RAHCWECPMVQPPERTIRGPAELFR TPTLSGWLPPELLGLWTHCAQPPPK ALRRELPEEAAAEEERRKIEVPSEI EVPREALEPSVPLMVSLEISLEAAE EEKSRISLIPPEERWAWPEVEAPEA PALPVVPELPEVPMEMPLVLPPELE LLSLEAVHRAVALELQANREPDFSS LVSPLSPRRMAARVFYLLLVLSAQQ ILHVKQEKPYGRLLIQPGPRFHTRT RPLEQKLISEEDLAANDILDYKDDD DKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: REC8 REC8 meiotic recombination protein [ Homo sapiens (human) ]
• Official Symbol: REC8
• Synonyms: REC8; REC8 homolog (yeast); REC8 like 1 (yeast), REC8L1; meiotic recombination protein REC8 homolog; Rec8p; REC8-like 1; cohesin Rec8p; cohesion rec8p; human homolog of rad21, S. pombe; meiotic recombination protein REC8-like 1; recombination and sister chromatid cohesion protein homolog; meiotic recombination and sister chromatid cohesion phosphoprotein of the rad21p family; REC8L1; HR21spB; MGC950
• Gene ID: 9985
• mRNA Refseq: NM_005132
• Protein Refseq: NP_005123
• MIM: 608193
• UniProt ID: O95072