Recombinant Human RELA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RELA-2484H
• Product Overview: RELA MS Standard C13 and N15-labeled recombinant protein (NP_068810) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: NF-kappa-B is a ubiquitous transcription factor involved in several biological processes. It is held in the cytoplasm in an inactive state by specific inhibitors. Upon degradation of the inhibitor, NF-kappa-B moves to the nucleus and activates transcription of specific genes. NF-kappa-B is composed of NFKB1 or NFKB2 bound to either REL, RELA, or RELB. The most abundant form of NF-kappa-B is NFKB1 complexed with the product of this gene, RELA. Four transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 60 kDa
• AA Sequence: MDELFPLIFPAEPAQASGPYVEIIE QPKQRGMRFRYKCEGRSAGSIPGER STDTTKTHPTIKINGYTGPGTVRIS LVTKDPPHRPHPHELVGKDCRDGFY EAELCPDRCIHSFQNLGIQCVKKRD LEQAISQRIQTNNNPFQVPIEEQRG DYDLNAVRLCFQVTVRDPSGRPLRL PPVLSHPIFDNRAPNTAELKICRVN RNSGSCLGGDEIFLLCDKVQKEDIE VYFTGPGWEARGSFSQADVHRQVAI VFRTPPYADPSLQAPVRVSMQLRRP SDRELSEPMEFQYLPDTDDRHRIEE KRKRTYETFKSIMKKSPFSGPTDPR PPPRRIAVPSRSSASVPKPAPQPYP FTSSLSTINYDEFPTMVFPSGQISQ ASALAPAPPQVLPQAPAPAPAPAMV SALAQAPAPVPVLAPGPPQAVAPPA PKPTQAGEGTLSEALLQLQFDDEDL GALLGNSTDPAVFTDLASVDNSEFQ QLLNQGIPVAPHTTEPMLMEYPEAI TRLVTGAQRPPDPAPAPLGAPGLPN GLLSGDEDFSSIADMDFSALLSQIS STRTRPLEQKLISEEDLAANDILDY KDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RELA RELA proto-oncogene, NF-kB subunit [ Homo sapiens (human) ]
• Official Symbol: RELA
• Synonyms: RELA; v-rel reticuloendotheliosis viral oncogene homolog A (avian); NFKB3, nuclear factor of kappa light polypeptide gene enhancer in B cells 3; transcription factor p65; p65; NF-kappa-B p65delta3; nuclear factor NF-kappa-B p65 subunit; nuclear factor of kappa light polypeptide gene enhancer in B-cells 3; NFKB3; MGC131774
• Gene ID: 5970
• mRNA Refseq: NM_021975
• Protein Refseq: NP_068810
• MIM: 164014
• UniProt ID: Q04206