| Description : |
Regulates intracellular cholesterol distribution from recycling endosomes to the trans-Golgi network through interactions with RAB11 and OSBP. Functions in membrane tethering and promotes OSBP-mediated cholesterol transfer between RAB11-bound recycling endosomes and OSBP-bound Golgi-like membranes. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
134.4 kDa |
| AA Sequence : |
MAAMAPGGSGSGGGVNPFLSDSDED DDEVAATEERRAVLRLGAGSGLDPG SAGSLSPQDPVALGSSARPGLPGEA SAAAVALGGTGETPARLSIDAIAAQ LLRDQYLLTALELHTELLESGRELP RLRDYFSNPGNFERQSGTPPGMGAP GVPGAAGVGGAGGREPSTASGGGQL NRAGSISTLDSLDFARYSDDGNRET DEKVAVLEFELRKAKETIQALRANL TKAAEHEVPLQERKNYKSSPEIQEP IKPLEKRALNFLVNEFLLKNNYKLT SITFSDENDDQDFELWDDVGLNIPK PPDLLQLYRDFGNHQVTGKDLVDVA SGVEEDELEALTPIISNLPPTLETP QPAENSMLVQKLEDKISLLNSEKWS LMEQIRRLKSEMDFLKNEHFAIPAV CDSVQPPLDQLPHKDSEDSGQHPDV NSSDKGKNTDIHLSISDEADSTIPK ENSPNSFPRREREGMPPSSLSSKKT VHFDKPNRKLSPAFHQALLSFCRMS ADSRLGYEVSRIADSEKSVMLMLGR CLPHIVPNVLLAKREELIPLILCTA CLHPEPKERDQLLHILFNLIKRPDD EQRQMILTGCVAFARHVGPTRVEAE LLPQCWEQINHKYPERRLLVAESCG ALAPYLPKEIRSSLVLSMLQQMLME DKADLVREAVIKSLGIIMGYIDDPD KYHQGFELLLSALGDPSERVVSATH QVFLPAYAAWTTELGNLQSHLILTL LNKIEKLLREGEHGLDEHKLHMYLS ALQSLIPSLFALVLQNAPFSSKAKL HGEVPQIEVTRFPRPMSPLQDVSTI IGSREQLAVLLQLYDYQLEQEGTTG WESLLWVVNQLLPQLIEIVGKINVT STACVHEFSRFFWRLCRTFGKIFTN TKVKPQFQEILRLSEENIDSSAGNG VLTKATVPIYATGVLTCYIQEEDRK LLVGFLEDVMTLLSLSHAPLDSLKA SFVELGANPAYHELLLTVLWYGVVH TSALVRCTAARMFELTLRGMSEALV DKRVAPALVTLSSDPEFSVRIATIP AFGTIMETVIQRELLERVKMQLASF LEDPQYQDQHSLHTEIIKTFGRVGP NAEPRFRDEFVIPHLHKLALVNNLQ IVDSKRLDIATHLFEAYSALSCCFI SEDLMVNHFLPGLRCLRTDMEHLSP EHEVILSSMIKECEQKVENKTVQEP QGSMSIAASLVSEDTKTKFLNKMGQ LTTSGAMLANVFQRKKTRTRPLEQK LISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
