Recombinant Mouse Relch Protein, Myc/DDK-tagged

• Cat.No.: Relch-5458M
• Product Overview: Purified recombinant protein of mouse full-length RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing (Relch), with C-terminal MYC/DDK tag, expressed in HEK293T cells.

Specification

• Species: Mouse
• Source: HEK293
• Tag: DDK&Myc
• Description: Regulates intracellular cholesterol distribution from recycling endosomes to the trans-Golgi network through interactions with RAB11 and OSBP. Functions in membrane tethering and promotes OSBP-mediated cholesterol transfer between RAB11-bound recycling endosomes and OSBP-bound Golgi-like membranes.
• Molecular Mass: 134.6 kDa
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 12 months from the date of receipt of the product under proper storage and handling conditions. Avoid repeated freeze-thaw cycles.
• Storage: Store at -80 centigrade after receiving vials.
• Concentration: >50 μg/mL as determined by microplate BCA method
• Storage Buffer: 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.

Gene Information

• Gene Name: Relch RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing [ Mus musculus (house mouse) ]
• Official Symbol: Relch
• Synonyms: Relch; RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing; Kiaa1468; mKIAA1468; 6430401N10; 2310035C23Rik; RAB11-binding protein RELCH; RAB11-binding protein containing LisH, coiled-coil, and HEAT repeats
• Gene ID: 227446
• mRNA Refseq: NM_173187
• Protein Refseq: NP_775279
• UniProt ID: Q148V7