Recombinant Human RGS10 Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RGS10-4835H
• Product Overview: RGS10 MS Standard C13 and N15-labeled recombinant protein (NP_002916) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Regulator of G protein signaling (RGS) family members are regulatory molecules that act as GTPase activating proteins (GAPs) for G alpha subunits of heterotrimeric G proteins. RGS proteins are able to deactivate G protein subunits of the Gi alpha, Go alpha and Gq alpha subtypes. They drive G proteins into their inactive GDP-bound forms. Regulator of G protein signaling 10 belongs to this family. All RGS proteins share a conserved 120-amino acid sequence termed the RGS domain. This protein associates specifically with the activated forms of the two related G-protein subunits, G-alphai3 and G-alphaz but fails to interact with the structurally and functionally distinct G-alpha subunits. Regulator of G protein signaling 10 protein is localized in the nucleus. Two transcript variants encoding different isoforms have been found for this gene.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 19.4 kDa
• AA Sequence: MEHIHDSDGSSSSSHQSLKSTAKWA ASLENLLEDPEGVKRFREFLKKEFS EENVLFWLACEDFKKMQDKTQMQEK AKEIYMTFLSSKASSQVNVEGQSRL NEKILEEPHPLMFQKLQDQIFNLMK YDSYSRFLKSDLFLKHKRTEEEEED LPDAQTAAKRASRIYNTTRTRPLEQ KLISEEDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RGS10 regulator of G-protein signaling 10 [ Homo sapiens (human) ]
• Official Symbol: RGS10
• Synonyms: RGS10; regulator of G-protein signaling 10; regulator of G protein signalling 10; regulator of G-protein signalling 10
• Gene ID: 6001
• mRNA Refseq: NM_002925
• Protein Refseq: NP_002916
• MIM: 602856
• UniProt ID: O43665