| Description : |
This gene belongs to the RING finger family, members of which encode proteins characterized by a RING domain, a zinc-binding motif related to the zinc finger domain. The gene product can bind DNA and can act as a transcriptional repressor. It is associated with the multimeric polycomb group protein complex. The gene product interacts with the polycomb group proteins BMI1, EDR1, and CBX4, and colocalizes with these proteins in large nuclear domains. It interacts with the CBX4 protein via its glycine-rich C-terminal domain. The gene maps to the HLA class II region, where it is contiguous with the RING finger genes FABGL and HKE4. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
42.4 kDa |
| AA Sequence : |
MTTPANAQNASKTWELSLYELHRTP QEAIMDGTEIAVSPRSLHSELMCPI CLDMLKNTMTTKECLHRFCSDCIVT ALRSGNKECPTCRKKLVSKRSLRPD PNFDALISKIYPSREEYEAHQDRVL IRLSRLHNQQALSSSIEEGLRMQAM HRAQRVRRPIPGSDQTTTMSGGEGE PGEGEGDGEDVSSDSAPDSAPGPAP KRPRGGGAGGSSVGTGGGGTGGVGG GAGSEDSGDRGGTLGGGTLGPPSPP GAPSPPEPGGEIELVFRPHPLLVEK GEYCQTRYVKTTGNATVDHLSKYLA LRIALERRQQQEAGEPGGPGGGASD TGGPDGCGGEGGGAGGGDGPEEPAL PSLEGVSEKQYTIYIAPGGGAFTTL NGSLTLELVNEKFWKVSRPLELCYA PTKDPKTRTRPLEQKLISEEDLAAN DILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
