Recombinant Human RNASEH2B Protein, Myc/DDK-tagged, C13 and N15-labeled
Cat.No. : | RNASEH2B-1331H |
Product Overview : | RNASEH2B MS Standard C13 and N15-labeled recombinant protein (NP_001135751) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells. |
- Specification
- Gene Information
- Related Products
Description : | RNase H2 is composed of a single catalytic subunit (A) and two non-catalytic subunits (B and C) and specifically degrades the RNA of RNA:DNA hybrids. The protein encoded by this gene is the non-catalytic B subunit of RNase H2, which is thought to play a role in DNA replication. Multiple transcript variants encoding different isoforms have been found for this gene. Defects in this gene are a cause of Aicardi-Goutieres syndrome type 2 (AGS2). |
Source : | HEK293 |
Species : | Human |
Tag : | Myc/DDK |
Molecular Mass : | 28.8 kDa |
AA Sequence : | MAAGVDCGDGVGARQHVFLVSEYLK DASKKMKNGLMFVKLVNPCSGEGAI YLFNMCLQQLFEVKVFKEKHHSWFI NQSVQSGGLLHFATPVDPLFLLLHY LIKADKEGKFQPLDQVVVDNVFPNC ILLLKLPGLEKLLHHVTEEKGNPEI DNKKYYKYSKEKTLKWLEKKVNQTV AALKTNNVNVSSRVQSTAFFSGDQA STDKEEDYIRYAHGLISDYIPKELS DDLSKYLKLPEPSASLPNPPSKMAA QRQKRGKTRTRPLEQKLISEEDLAA NDILDYKDDDDKV |
Purity : | > 80% as determined by SDS-PAGE and Coomassie blue staining |
Stability : | Stable for 3 months from receipt of products under proper storage and handling conditions. |
Storage : | Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
Concentration : | 50 μg/mL as determined by BCA |
Storage Buffer : | 100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
Gene Name : | RNASEH2B ribonuclease H2 subunit B [ Homo sapiens (human) ] |
Official Symbol : | RNASEH2B |
Synonyms : | RNASEH2B; ribonuclease H2 subunit B; AGS2; DLEU8; ribonuclease H2 subunit B; Aicardi-Goutieres syndrome 2 protein; RNase H2 subunit B; deleted in lymphocytic leukemia 8; ribonuclease HI subunit B |
Gene ID : | 79621 |
mRNA Refseq : | NM_001142279 |
Protein Refseq : | NP_001135751 |
MIM : | 610326 |
UniProt ID : | Q5TBB1 |
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For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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