Recombinant Human RNF14 Protein, MYC/DDK-tagged

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Recombinant Human RNF14 Protein, MYC/DDK-tagged

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Cat.No. : RNF14-686H
Product Overview : Recombinant Human RNF14, transcript variant 4, fused with MYC/DDK tag at C-terminal was expressed in HEK293.
Description : The protein encoded by this gene contains a RING zinc finger, a motif known to be involved in protein-protein interactions. This protein interacts with androgen receptor (AR) and may function as a coactivator that induces AR target gene expression in prostate. A dominant negative mutant of this gene has been demonstrated to inhibit the AR-mediated growth of prostate cancer. This protein also interacts with class III ubiquitin-conjugating enzymes (E2s) and may act as a ubiquitin-ligase (E3) in the ubiquitination of certain nuclear proteins. Six alternatively spliced transcript variants encoding two distinct isoforms have been reported.
Source : HEK293
Species : Human
Tag : MYC/DDK
Form : 25 mM Tris.HCl, pH 7.3, 100 mM glycine, 10% glycerol.
Molecular Mass : 53.7 kDa
Purity : > 80% as determined by SDS-PAGE and Coomassie blue staining
Concentration : >50 ug/mL as determined by microplate BCA method
Gene Name : RNF14 ring finger protein 14 [ Homo sapiens ]
Official Symbol : RNF14
Synonyms : RNF14; ring finger protein 14; E3 ubiquitin-protein ligase RNF14; ARA54; HFB30; TRIAD2; androgen receptor associated protein 54; androgen receptor-associated protein 54; HRIHFB2038; FLJ26004;
Gene ID : 9604
mRNA Refseq : NM_183400
Protein Refseq : NP_899647
MIM : 605675
UniProt ID : Q9UBS8
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.

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