| Description : |
The protein encoded by this gene belongs to the ROBO family, part of the immunoglobulin superfamily of proteins that are highly conserved from fly to human. The encoded protein is a transmembrane receptor for the slit homolog 2 protein and functions in axon guidance and cell migration. Mutations in this gene are associated with vesicoureteral reflux, characterized by the backward flow of urine from the bladder into the ureters or the kidney. Alternative splicing results in multiple transcript variants. |
| Source : |
HEK293 |
| Species : |
Human |
| Tag : |
Myc/DDK |
| Molecular Mass : |
152.9 kDa |
| AA Sequence : |
MARRHERVTRRMWTWAPGLLMMTVV FWGHQGNGQGQGSRLRQEDFPPRIV EHPSDVIVSKGEPTTLNCKAEGRPT PTIEWYKDGERVETDKDDPRSHRML LPSGSLFFLRIVHGRRSKPDEGSYV CVARNYLGEAVSRNASLEVALLRDD FRQNPTDVVVAAGEPAILECQPPRG HPEPTIYWKKDKVRIDDKEERISIR GGKLMISNTRKSDAGMYTCVGTNMV GERDSDPAELTVFERPTFLRRPINQ VVLEEEAVEFRCQVQGDPQPTVRWK KDDADLPRGRYDIKDDYTLRIKKTM STDEGTYMCIAENRVGKMEASATLT VRAPPQFVVRPRDQIVAQGRTVTFP CETKGNPQPAVFWQKEGSQNLLFPN QPQQPNSRCSVSPTGDLTITNIQRS DAGYYICQALTVAGSILAKAQLEVT DVLTDRPPPIILQGPANQTLAVDGT ALLKCKATGDPLPVISWLKEGFTFP GRDPRATIQEQGTLQIKNLRISDTG TYTCVATSSSGETSWSAVLDVTESG ATISKNYDLSDLPGPPSKPQVTDVT KNSVTLSWQPGTPGTLPASAYIIEA FSQSVSNSWQTVANHVKTTLYTVRG LRPNTIYLFMVRAINPQGLSDPSPM SDPVRTQDISPPAQGVDHRQVQKEL GDVLVRLHNPVVLTPTTVQVTWTVD RQPQFIQGYRVMYRQTSGLQATSSW QNLDAKVPTERSAVLVNLKKGVTYE IKVRPYFNEFQGMDSESKTVRTTEE APSAPPQSVTVLTVGSYNSTSISVS WDPPPPDHQNGIIQEYKIWCLGNET RFHINKTVDAAIRSVIIGGLFPGIQ YRVEVAASTSAGVGVKSEPQPIIIG RRNEVVITENNNSITEQITDVVKQP AFIAGIGGACWVILMGFSIWLYWRR KKRKGLSNYAVTFQRGDGGLMSNGS RPGLLNAGDPSYPWLADSWPATSLP VNNSNSGPNEIGNFGRGDVLPPVPG QGDKTATMLSDGAIYSSIDFTTKTS YNSSSQITQATPYATTQILHSNSIH ELAVDLPDPQWKSSIQQKTDLMGFG YSLPDQNKGNNGGKGGKKKKNKNSS KPQKNNGSTWANVPLPPPPVQPLPG TELEHYAVEQQENGYDSDSWCPPLP VQTYLHQGLEDELEEDDDRVPTPPV RGVASSPAISFGQQSTATLTPSPRE EMQPMLQAHLDELTRAYQFDIAKQT WHIQSNNQPPQPPVPPLGYVSGALI SDLETDVADDDADDEEEALEIPRPL RALDQTPGSSMDNLDSSVTGKAFTS SQRPRPTSPFSTDSNTSAALSQSQR PRPTKKHKGGRMDQQPALPHRREGM TDEEALVPYSKPSFPSPGGHSSSGT ASSKGSTGPRKTEVLRAGHQRNASD LLDIGYMGSNSQGQFTGELTRTRPL EQKLISEEDLAANDILDYKDDDDKV |
| Purity : |
> 80% as determined by SDS-PAGE and Coomassie blue staining |
| Stability : |
Stable for 3 months from receipt of products under proper storage and handling conditions. |
| Storage : |
Store at -80 centigrade. Avoid repeated freeze-thaw cycles. |
| Concentration : |
50 μg/mL as determined by BCA |
| Storage Buffer : |
100 mM glycine, 25 mM Tris-HCl, pH 7.3. |
