Recombinant Human ROR1 protein, T7/His-tagged
Cat.No. : | ROR1-88H |
Product Overview : | Recombinant human ROR1 extracellular domain cDNA (30-406 aa) fused with T7-His-TEV cleavage site Tag (29aa) at N-terminal was expressed in E. coli. |
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Source : | E. coli |
Species : | Human |
Tag : | His&T7 |
Form : | 0.5 mg/ml, sterile-filtered, in 20 mM pH 8.0 Tris-HCl Buffer, with proprietary formulation of NaCl, KCl, EDTA, Sucrose, DTT. |
AA Sequence : | MASMTGGQQMGRGHHHHHHGNLYFQ GEFQETELSVSAELVPTSSWNISSE LNKDSYLTLDEPMNNITTSLGQTAE LHCKVSGNPPPTIRWFKNDAPVVQE PRRLSFRSTIYGSRLRIRNLDTTDT GYFQCVATNGKEVVSSTGVLFVKFG PPPTASPGYSDEYEEDGFCQPYRGI ACARFIGNRTVYMESLHMQGEIENQ ITAAFTMIGTSSHLSDKCSQFAIPS LCHYAFPYCDETSSVPKPRDLCRDE CEILENVLCQTEYIFARSNPMILMR LKLPNCEDLPQPESPEAANCIRIGI PMADPINKNHKCYNSTGVDYRGTVS VTKSGRQCQPWNSQYPHTHTFTALR FPELNGGHSYCRNPGNQKEAPWCFT LDENFKSDLCDIPACDSKDSKEKNK MEILY |
Purity : | >90% by SDS-PAGE |
Applications : | 1. May be used for in vitro ROR1 mediated T cell and neuronal cell differentiation regulation study with this protein either as soluble factor or as coating matrix protein.2. May be used for protein-protein interaction assay.3. Potential biomarker protein for cancer therapy applications.4. As antigen for specific antibody production. |
Storage : | Keep at -80centigrade for long term storage. Product is stable at 4 centigrade for at least 30 days. |
Gene Name : | ROR1 receptor tyrosine kinase-like orphan receptor 1 [ Homo sapiens ] |
Official Symbol : | ROR1 |
Synonyms : | ROR1; receptor tyrosine kinase-like orphan receptor 1; NTRKR1; tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase receptor-related 1; neurotrophic tyrosine kinase, receptor-related 1; dJ537F10.1; MGC99659; |
Gene ID : | 4919 |
mRNA Refseq : | NM_001083592 |
Protein Refseq : | NP_001077061 |
MIM : | 602336 |
UniProt ID : | Q01973 |
Chromosome Location : | 1p32-p31 |
Pathway : | Nuclear Receptors, organism-specific biosystem; |
Function : | ATP binding; Wnt-protein binding; kinase activity; nucleotide binding; receptor activity; transmembrane receptor protein tyrosine kinase activity; |
Products Types
◆ Lysates | ||
ROR1-002HCL | Recombinant Human ROR1 cell lysate | +Inquiry |
ROR1-001HCL | Recombinant Human ROR1 cell lysate | +Inquiry |
Related Gene
For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.
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Customer Reviews (3)
Write a reviewCustomer service promptly feedback my requests, technical staff timely solve the problems that arise.
Excellent after-sales service, solving many experimental problems.
Fast and timely shipment helped me to get satisfactory experimental results in short time.
Q&As (4)
Ask a questionROR1 is barely expressed in normal, differentiated and mature tissues, but is highly expressed in tumor tissues.
Inhibit the expression of ROR1 can reduce the proliferation and migration ability of tumor cells.
ROR1 is involved in the regulation of cell metabolism, proliferation, apoptosis, and differentiation.
ROR1 is involved in the study of breast, lung and ovarian cancers.
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