Recombinant Human RRM2 Protein

• Cat.No.: RRM2-69H
• Product Overview: Recombinant Human RRM2 Protein was expressed in E. coli.

Specification

• Description: This gene encodes one of two non-identical subunits for ribonucleotide reductase. This reductase catalyzes the formation of deoxyribonucleotides from ribonucleotides. Synthesis of the encoded protein (M2) is regulated in a cell-cycle dependent fashion. Transcription from this gene can initiate from alternative promoters, which results in two isoforms that differ in the lengths of their N-termini. Related pseudogenes have been identified on chromosomes 1 and X.
• Source: E. coli
• Species: Human
• Form: Liquid. In 20 mM Tris-HCl, 100 mM NaCl, pH 8.0, containing 10% glycerol.
• Molecular Mass: ~47.0 kDa
• AA Sequence: MGSSHHHHHHSSGLVPRGSHMLSLR VPLAPITDPQQLQLSPLKGLSLVDK ENTPPALSGTRVLASKTARRIFQEP TEPKTKAAAPGVEDEPLLRENPRRF VIFPIEYHDIWQMYQKAEASFWTAE EVDLSKDIQHWESLKPEERYFISHV LAFFAASDGIVNENLVERFSQEVQI TEARCFYGFQIAMENIHSEMYSLLI DTYIKDPKEREFLFNAIETMPCVKK KADWALRWIGDKEATYGERVVAFAA VEGIFFSGSFASIFWLKKRGLMPGL TFSNELISRDEGLHCDFACLMFKHL VHKPSEERVREIIINAVRIEQEFLT EALPVKLIGMNCTLMKQYIEFVADR LMLELGFSKVFRVENPFDFMENISL EGKTNFFEKRVGEYQRMGVMSSPTE NSFTLDADF
• Purity: >90%
• Storage: Short Term Storage at 4 centigrade, Long Term, please prepare aliquots with 20% glycerol and store at -20 to -80 centigrade. Avoid freeze/thaw cycles.
• Concentration: 0.1 mg/ml
• Official Full Name: Ribonucleotide reductase regulatory subunit M2

Gene Information

• Gene Name: RRM2 ribonucleotide reductase regulatory subunit M2 [ Homo sapiens (human) ]
• Official Symbol: RRM2
• Synonyms: R2; RR2; RR2M; C2orf48
• Gene ID: 6241
• mRNA Refseq: NM_001034
• Protein Refseq: NP_001025
• MIM: 180390
• UniProt ID: P31350