Recombinant Human RS1 protein, His & GST-tagged

• Cat.No.: RS1-1730H
• Product Overview: Recombinant Human RS1 aa. (Ser24~Ala224 (Accession # O15537)) fused with N-terminal His & GST tag was produced in E. coli cells.

Specification

• Species: Human
• Source: E.coli
• Tag: GST&His
• Protein Length: Ser24~Ala224
• Description: This gene encodes an extracellular protein that plays a crucial role in the cellular organization of the retina. The encoded protein is assembled and secreted from photoreceptors and bipolar cells as a homo-oligomeric protein complex. Mutations in this gene are responsible for X-linked retinoschisis, a common, early-onset macular degeneration in males that results in a splitting of the inner layers of the retina and severe loss in vision.
• Form: Freeze-dried powder
• Molecular Mass: Predicted Molecular Mass: 53.0kDa
• Endotoxin: <1.0EU per 1ug (determined by the LAL method)
• Purity: >90%
• Applications: SDS-PAGE; WB; ELISA; IP.
• Stability: The thermal stability is described by the loss rate. The loss rate was determined by accelerated thermal degradation test, that is, incubate the protein at 37°C for 48h, and no obvious degradation and precipitation were observed. The loss rate is less than 5% within the expiration date under appropriate storage condition.
• Storage: Avoid repeated freeze/thaw cycles. Store at 2-8°C for one month. Aliquot and store at -80°C for 12 months.
• Storage buffer: Supplied as lyophilized form in PBS, pH7.4, containing 5% trehalose, 0.01% sarcosyl.
• Reconstitution: Reconstitute in sterile PBS, pH7.2-pH7.4.
• Isoelectric Point: 5.5

Gene Information

• Gene Name: RS1 retinoschisin 1 [ Homo sapiens (human) ]
• Official Symbol: RS1
• Synonyms: RS1; retinoschisin 1; RS; XLRS1; X-linked juvenile retinoschisis protein
• Gene ID: 6247
• mRNA Refseq: NM_000330.3
• Protein Refseq: NP_000321.1
• UniProt ID: O15537