Recombinant Human RSPO1 Protein, SER21-ALA263, Tag Free, Biotinylated

• Cat.No.: RSPO1-214H
• Product Overview: Recombinant human R-Spondin1 protein was developed from HEK293.

Specification

• Species: Human
• Source: HEK293
• Tag: Non
• Protein Length: SER21-ALA263
• Description: This gene encodes a secreted activator protein with two cysteine-rich, furin-like domains and one thrombospondin type 1 domain. The encoded protein is a ligand for leucine-rich repeat-containing G-protein coupled receptors (LGR proteins) and positively regulates the Wnt signaling pathway. In mice, the protein induces the rapid onset of crypt cell proliferation and increases intestinal epithelial healing, providing a protective effect against chemotherapy-induced adverse effects. Alternative splicing results in multiple transcript variants.
• Conjugation/Label: Biotin
• Form: Lyophilised
• Endotoxin: Endotoxin level was found to be less than 0.1 ng/μg (1 EU/μg).
• Applications: ELISA, WB
• Notes: FOR RESEARCH USE ONLY (RUO).
• Storage: Recombinant R-spondin1can be stored in working aliquots at 2 to 8 centigrade for one month, or at -20 to -70 centigrade for 1 year. Avoid repeated freeze/thaw cycles.
• Storage Buffer: Lyophilised from 0.2 μm filtered PBS solution, pH 7.2, 5% Trehalose.
• Conjugation: Biotin

Gene Information

• Gene Name: RSPO1 R-spondin 1 [ Homo sapiens (human) ]
• Official Symbol: RSPO1
• Synonyms: RSPO1; R-spondin 1; R spondin homolog (Xenopus laevis); R-spondin-1; FLJ40906; RSPONDIN; R-spondin homolog; roof plate-specific spondin-1; RSPO; CRISTIN3; RP11-566C13.1
• Gene ID: 284654
• mRNA Refseq: NM_001038633
• Protein Refseq: NP_001033722
• MIM: 609595
• UniProt ID: Q2MKA7