Recombinant Human RXRA protein, His-tagged

• Cat.No.: RXRA-20H
• Product Overview: Recombinant Human RXRA fused with His tag was expressed in E. coli.

Specification

• Source: E. coli
• Species: Human
• Tag: His
• Form: The protein is in 20mM Tris-HCl pH7.9,100mM NaCl, 0.2mM EDTA, 1mM DTT and 20% glycerol. Stored at -70 centigrade before use. Avoid repeated freeze thaw cycles.
• Molecular Mass: 53.3 kDa
• AA Sequence: MDTKHFLPLD FSTQVNSSLT SPTGRGSMAA PSLHPSLGPG IGSPGQLHSP ISTLSSPINGMGPPFSVISS PMGPHSMSVP TTPTLGFSTG SPQLSSPMNP VSSSEDIKPP LGLNGVLKVPAHPSGNMASF TKHICAICGD RSSGKHYGVY SCEGCKGFFK RTVRKDLTYT CRDNKDCLIDKRQRNRCQYC RYQKCLAMGM KREAVQEERQ RGKDRNENEV ESTSSANEDM PVERILEAELAVEPKTETYV EANMGLNPSS PNDPVTNICQ AADKQLFTLV EWAKRIPHFS ELPLDDQVILLRAGWNELLI ASFSHRSIAV KDGILLATGL HVHRNSAHSA GVGAIFDRVL TELVSKMRDMQMDKTELGCL RAIVLFNPDS KGLSNPAEVE ALREKVYASL EAYCKHKYPE QPGRFAKLLLRLPALRSIGL KCLEHLFFFK LIGDTPIDTF LMEMLEAPHQ MT
• Purity: > 90%
• Unit Definition: 1 unit equals 1 nanogram of purified protein. 1 unit is sufficient for a gel mobility shift assay in a 20 µl reaction; 100 units are sufficient for protein-protein interaction assays.
• Applications: RXRα can be applied in reconstituted in vitro transcription assays and protein-protein interactions assays.

Gene Information

• Gene Name: RXRA retinoid X receptor, alpha [ Homo sapiens ]
• Official Symbol: RXRA
• Synonyms: RXRA; retinoid X receptor, alpha; retinoic acid receptor RXR-alpha; NR2B1; nuclear receptor subfamily 2 group B member 1; retinoid X nuclear receptor alpha; FLJ00280; FLJ00318; FLJ16020; FLJ16733; MGC102720
• Gene ID: 6256
• mRNA Refseq: NM_002957
• Protein Refseq: NP_002948
• MIM: 180245
• UniProt ID: P19793
• Chromosome Location: 9q34
• Pathway: Adipocytokine signaling pathway, organism-specific biosystem; Adipocytokine signaling pathway, conserved biosystem; Adipogenesis, organism-specific biosystem; BMAL1:CLOCK/NPAS2 Activates Circadian Expression, organism-specific biosystem; Bile secretion, organism-specific biosystem; Bile secretion, conserved biosystem; Circadian Clock, organism-specific biosystem
• Function: 9-cis retinoic acid receptor activity; DNA binding; double-stranded DNA binding; enzyme binding; ligand-activated sequence-specific DNA binding RNA polymerase II transcription factor activity; metal ion binding; protein binding; protein heterodimerization activity; receptor activity; retinoic acid receptor activity; retinoic acid-responsive element binding; sequence-specific DNA binding; sequence-specific DNA binding transcription factor activity; contributes_to sequence-specific DNA binding transcription factor activity; steroid binding; steroid hormone receptor activity; transcription coactivator activity; contributes_to transcription regulatory region DNA binding; vitamin D receptor binding; contributes_to vitamin D response element binding; zinc ion binding