Recombinant Human RXRA Protein, Myc/DDK-tagged, C13 and N15-labeled

• Cat.No.: RXRA-4137H
• Product Overview: RXRA MS Standard C13 and N15-labeled recombinant protein (NP_002948) with a C-terminal MYC/DDK tag, was expressed in HEK293 cells.

Specification

• Description: Retinoid X receptors (RXRs) and retinoic acid receptors (RARs) are nuclear receptors that mediate the biological effects of retinoids by their involvement in retinoic acid-mediated gene activation. These receptors function as transcription factors by binding as homodimers or heterodimers to specific sequences in the promoters of target genes. The protein encoded by this gene is a member of the steroid and thyroid hormone receptor superfamily of transcriptional regulators. Alternative splicing of this gene results in multiple transcript variants.
• Source: HEK293
• Species: Human
• Tag: Myc/DDK
• Molecular Mass: 50.6 kDa
• AA Sequence: MDTKHFLPLDFSTQVNSSLTSPTGR GSMAAPSLHPSLGPGIGSPGQLHSP ISTLSSPINGMGPPFSVISSPMGPH SMSVPTTPTLGFSTGSPQLSSPMNP VSSSEDIKPPLGLNGVLKVPAHPSG NMASFTKHICAICGDRSSGKHYGVY SCEGCKGFFKRTVRKDLTYTCRDNK DCLIDKRQRNRCQYCRYQKCLAMGM KREAVQEERQRGKDRNENEVESTSS ANEDMPVERILEAELAVEPKTETYV EANMGLNPSSPNDPVTNICQAADKQ LFTLVEWAKRIPHFSELPLDDQVIL LRAGWNELLIASFSHRSIAVKDGIL LATGLHVHRNSAHSAGVGAIFDRVL TELVSKMRDMQMDKTELGCLRAIVL FNPDSKGLSNPAEVEALREKVYASL EAYCKHKYPEQPGRFAKLLLRLPAL RSIGLKCLEHLFFFKLIGDTPIDTF LMEMLEAPHQMTTRTRPLEQKLISE EDLAANDILDYKDDDDKV
• Purity: > 80% as determined by SDS-PAGE and Coomassie blue staining
• Stability: Stable for 3 months from receipt of products under proper storage and handling conditions.
• Storage: Store at -80 centigrade. Avoid repeated freeze-thaw cycles.
• Concentration: 50 μg/mL as determined by BCA
• Storage Buffer: 100 mM glycine, 25 mM Tris-HCl, pH 7.3.

Gene Information

• Gene Name: RXRA retinoid X receptor alpha [ Homo sapiens (human) ]
• Official Symbol: RXRA
• Synonyms: RXRA; retinoid X receptor, alpha; retinoic acid receptor RXR-alpha; NR2B1; nuclear receptor subfamily 2 group B member 1; retinoid X nuclear receptor alpha; FLJ00280; FLJ00318; FLJ16020; FLJ16733; MGC102720
• Gene ID: 6256
• mRNA Refseq: NM_002957
• Protein Refseq: NP_002948
• MIM: 180245
• UniProt ID: P19793