Recombinant Human RYK

Cat.No. : RYK-31340TH
Product Overview : Recombinant fragment of Human RYK with N terminal proprietary tag, 37.73kDa.
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Description : The protein encoded by this gene is an atypical member of the family of growth factor receptor protein tyrosine kinases, differing from other members at a number of conserved residues in the activation and nucleotide binding domains. This gene product belongs to a subfamily whose members do not appear to be regulated by phosphorylation in the activation segment. It has been suggested that mediation of biological activity by recruitment of a signaling-competent auxiliary protein may occur through an as yet uncharacterized mechanism. Two alternative splice variants have been identified, encoding distinct isoforms.
Protein length : 110 amino acids
Molecular Weight : 37.730kDa inclusive of tags
Source : Wheat germ
Tissue specificity : Observed in all the tissues examined.
Form : Liquid
Purity : Proprietary Purification
Storage buffer : pH: 8.00Constituents:0.3% Glutathione, 0.79% Tris HCl
Storage : Shipped on dry ice. Upon delivery aliquot and store at -80oC. Avoid freeze / thaw cycles.
Sequences of amino acids : ELQSASAGPSVSLYLSEDEVRRLIGLDAELYYVRNDLISH YALSFSLLVPSETNFLHFTWHAKSKVEYKLGFQVDNVLAM DMPQVNISVQGEVPRTLSVFRVELSCTGKV
Sequence Similarities : Belongs to the protein kinase superfamily. Tyr protein kinase family.Contains 1 protein kinase domain.Contains 1 WIF domain.
Tag : Non
Gene Name : RYK RYK receptor-like tyrosine kinase [ Homo sapiens ]
Official Symbol : RYK
Synonyms : RYK; RYK receptor-like tyrosine kinase; JTK5A, JTK5A protein tyrosine kinase; tyrosine-protein kinase RYK; D3S3195; JTK5; RYK1;
Gene ID : 6259
mRNA Refseq : NM_002958
Protein Refseq : NP_002949
MIM : 600524
Uniprot ID : P34925
Chromosome Location : 3q22.1
Pathway : Wnt signaling network, organism-specific biosystem;
Function : ATP binding; Wnt-protein binding; frizzled binding; nucleotide binding; protein binding;

Not For Human Consumption!

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