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Recombinant Human S100 Calcium Bbinding Protein A4, His-tagged

Cat.No. : S100A4-409H
Product Overview : Recombinant human S100A4 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography, 13.8 kDa (121aa).
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Cat. No. : S100A4-409H
Description : S100A4, also known as S100 calcium-binding protein A4, belongs to the S100 super-family of proteins containing 2 EF-hand calcium binding domains. This protein is ubiquitously overexpressed and is localized in the cytoplasm and/or nucleus. S100A4 may play a role in motility, invasion, and tubulin polymerization. Chromosomal rearrangements and altered expression of the S100A4 gene have been implicated in tumor metastasis.
Source : Escherichia Coli.
Form : Liquid. In 20 mM Tris-HCl buffer (pH 8.0) containing 10% glycerol.
Purity : > 95% by SDS - PAGE
Concentration : 1 mg/ml (determined by Bradford assay).
Storage : Can be stored at +4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
Gene Name : S100A4 S100 calcium binding protein A4 [ Homo sapiens ]
Synonyms : 18A2; 42A; CAPL; FSP1; MTS1; P9KA; PEL98; Metastasin; S100 calcium-binding protein A4; fibroblast-specific protein-1; malignant transformation suppression 1; leukemia multidrug resistance associated protein; S100 calcium binding protein A4 (calcium protein, calvasculin, metastasin, murine placental homolog); Calvasculin; OTTHUMP00000015467; OTTHUMP00000015468; OTTHUMP00000015469; OTTHUMP00000032895; Placental calcium-binding protein; Protein Mts1; S100 calcium binding protein A4; S100 calcium-binding protein A4 (calcium protein,calvasculin, metastasin, murine placental homolog).
Gene ID : 6275
mRNA Refseq : NM_002961
Protein Refseq : NP_002952
MIM : 114210
UniProt ID : P26447
Chromosome Location : 1q21
Function : calcium ion binding, identical protein binding

For Research Use Only. Not intended for any clinical use. No products from Creative BioMart may be resold, modified for resale or used to manufacture commercial products without prior written approval from Creative BioMart.


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Q&As (6)

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What is the current progress in drug development for S100A4? 04/28/2022

Drug development for S100A4 is currently in clinical trials, including small molecule inhibitors against S100A4 and inhibitors against the S100A4 signaling pathway.

Is the expression of S100A4 affected by environmental factors? 11/08/2021

Yes, the expression of S100A4 is affected by environmental factors, such as nutritional status, inflammation level, etc.

What role does S100A4 play in tumor immunotherapy? 08/10/2021

S100A4 plays an important role in tumor immunotherapy, it can act as a tumor-associated antigen, activate the immune response of tumor cells, promote apoptosis of tumor cells and inhibit the proliferation of tumor cells.

How to improve the nutritional status of S100A4 protein through diet? 02/19/2021

There is no conclusive evidence that diet improves the nutritional status of S100A4 protein, but maintaining a balanced diet and moderate protein intake can help maintain good health.

How can S100A4 be used as a biomarker in clinical practice? 01/22/2020

In clinical practice, the expression level of S100A4 can be detected to predict disease progression and prognosis, and to guide the choice of treatment regimen. For example, in the diagnosis and treatment of oncological diseases.

What is the relationship between S100A4 protein and muscle wasting? 12/31/2019

Studies have shown that S100A4 protein can inhibit the occurrence of muscle wasting, but the specific mechanism is not clear.

Customer Reviews (3)

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    I have been using these for several years and they have been very stable and I swear by this product.


      The experimental process is simple and there is no special environmental requirement.


        It can remain stable under different temperature and pH conditions.

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