Recombinant Human S100 Calcium Binding Protein A11, His-tagged
Cat.No. : | S100A11-5480H |
Product Overview : | Recombinant HumanS100A11 is expressed in E. coli having a molecular weight of 17kDa fused toan amino terminal hexahistidine tag. |
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Cat. No. : | S100A11-5480H |
Description : | Protein S100A11 is a protein that in humans is encoded bythe S100A11 gene. The protein encoded by this gene is a member of the S100A11family of proteins containing 2 EF-hand calcium-binding motifs. S100A11proteins are localized in the cytoplasm and/or nucleus of a wide range ofcells, and involved in the regulation of a number of cellular processes suchas cell cycle progression and differentiation. |
Source : | E. coli |
Species : | Human |
Form : | The protein isconcentrated in a liquid (1.96 mg/ml) containing in PBS/50% glycerol. |
Purity : | Greater than95%(SDS-PAGE).2 bands on Western blot at 17 and 34 kDa,respectively representingmonomeric and dimeric form. |
Molecular Weight : | 17 kDa |
Storage : | Store at 2-4°C ifentire vial will be used within 1-2 weeks. Store, frozen at -20°C forlonger periods oftime. Please avoid freeze-thaw cycles. |
OfficialSymbol : | S100A11 |
Gene Name : | S100A11 S100 calcium bindingprotein A11 [ Homo sapiens ] |
Synonyms : | S100A11;S100 calcium binding protein A11; MLN70; S100C; proteinS100-A11; calgizzarin; protein S100-C; metastatic lymph node gene 70 protein;S100 calcium-binding protein A11 (calgizzarin); ProteinS100-A11; Calgizzarin; Metastatic lymph nodegene 70 protein; Protein S100-C; OTTHUMP00000015271 |
Gene ID : | 6282 |
mRNA Refseq : | NM_005620 |
Protein Refseq : | NP_005611 |
MIM : | 603114 |
UniProt ID : | P31949 |
Chromosome Location : | 1q21 |
Function : | S100 beta binding; calciumion binding; calcium-dependent protein binding; protein binding; proteinhomodimerization activity |
Products Types
◆ Recombinant Protein | ||
S100A11-1935H | Recombinant Human S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100a11-5665M | Recombinant Mouse S100a11 Protein, Myc/DDK-tagged | +Inquiry |
S100A11-7865M | Recombinant Mouse S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A11-4870R | Recombinant Rat S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A11-8373Z | Recombinant Zebrafish S100A11 | +Inquiry |
◆ Native Protein | ||
S100A11-3111H | Native Human S100A11 protein(Met1-Thr105) | +Inquiry |
◆ Lysates | ||
S100A11-2095HCL | Recombinant Human S100A11 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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Q&As (5)
Ask a questionS100A11 participates in multiple signaling pathways, influencing cancer progression and metastasis. It interacts with proteins involved in cell motility, invasion, and angiogenesis, contributing to the malignant phenotype.
S100A11 plays a role in cellular differentiation, influencing specific target genes and pathways. Its involvement in differentiation programs is context-dependent and varies across cell types.
S100A11 expression is regulated at transcriptional and post-translational levels. Transcription factors and signaling pathways control its mRNA levels, while post-translational modifications such as phosphorylation modulate its activity.
Emerging evidence suggests a potential role for S100A11 in neurodegenerative diseases. The mechanisms linking S100A11 to neurological pathology involve its interactions with proteins and signaling cascades.
S100A11 is a member of the S100 protein family, predominantly located in the cytoplasm and nucleus. Its physiological roles include regulation of cell proliferation, differentiation, and apoptosis.
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