Recombinant Human S100A11 protein, His-tagged
Cat.No. : | S100A11-3441H |
Product Overview : | Recombinant Human S100A11(1-105aa) fused with His tag at N-terminal was expressed in E. coli. |
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Description : | S100A11 is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. This protein may function in motility, invasion, and tubulin polymerization. |
Source : | E. coli |
Species : | Human |
Tag : | His |
Form : | Liquid. 20mM Tris-HCl buffer (pH8.0) containing 30% glycerol, 0.1M NaCl, 1mM DTT |
Molecular Mass : | 14.2kDa (128aa) confirmed by MALDI-TOF |
AA Sequence : | MGSSHHHHHH SSGLVPRGSH MGSHLDTNSDGQLD FSEFLNLIGG LAMACHDSFL KAVPSQKRT MAKISS PTETERCIES LIAVFQKYAG KDGYNYTLSK TEFLSFMNTE LAAFTKNQKD PGVLDRMMKK |
Purity : | >95% by SDS - PAGE |
Storage : | Can be stored at +4 centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20 centigrade or -70 centigrade. Avoid repeated freezing and thawing cycles. |
Concentration : | 1.0 mg/ml (determined by BCA assay) |
Protein length : | 1-105 |
Gene Name : | S100A11 S100 calcium binding protein A11 [ Homo sapiens ] |
Official Symbol : | S100A11 |
Synonyms : | S100A11; S100 calcium binding protein A11; S100 calcium binding protein A11 (calgizzarin) , S100 calcium binding protein A11 (calgizzarin); protein S100-A11; S100C; MLN 70; calgizzarin; protein S100-C; metastatic lymph node gene 70 protein; S100 calcium-binding protein A11 (calgizzarin); MLN70; |
Gene ID : | 6282 |
mRNA Refseq : | NM_005620 |
Protein Refseq : | NP_005611 |
MIM : | 603114 |
UniProt ID : | P31949 |
Chromosome Location : | 1q21 |
Function : | S100 beta binding; calcium ion binding; calcium-dependent protein binding; protein binding; protein homodimerization activity; |
Products Types
◆ Recombinant Protein | ||
S100A11-7865M | Recombinant Mouse S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A11-1935H | Recombinant Human S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100a11-5665M | Recombinant Mouse S100a11 Protein, Myc/DDK-tagged | +Inquiry |
S100A11-4870R | Recombinant Rat S100A11 Protein, His (Fc)-Avi-tagged | +Inquiry |
S100A11-5480H | Recombinant Human S100 Calcium Binding Protein A11, His-tagged | +Inquiry |
◆ Native Protein | ||
S100A11-3111H | Native Human S100A11 protein(Met1-Thr105) | +Inquiry |
◆ Lysates | ||
S100A11-2095HCL | Recombinant Human S100A11 293 Cell Lysate | +Inquiry |
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Not For Human Consumption!
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Q&As (5)
Ask a questionS100A11 participates in multiple signaling pathways, influencing cancer progression and metastasis. It interacts with proteins involved in cell motility, invasion, and angiogenesis, contributing to the malignant phenotype.
S100A11 plays a role in cellular differentiation, influencing specific target genes and pathways. Its involvement in differentiation programs is context-dependent and varies across cell types.
S100A11 expression is regulated at transcriptional and post-translational levels. Transcription factors and signaling pathways control its mRNA levels, while post-translational modifications such as phosphorylation modulate its activity.
Emerging evidence suggests a potential role for S100A11 in neurodegenerative diseases. The mechanisms linking S100A11 to neurological pathology involve its interactions with proteins and signaling cascades.
S100A11 is a member of the S100 protein family, predominantly located in the cytoplasm and nucleus. Its physiological roles include regulation of cell proliferation, differentiation, and apoptosis.
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