Recombinant Human S100A3, His-tagged

• Cat.No.: S100A3-3541H
• Product Overview: Recombinant humanS100A3 protein, fused to His-tag at N-terminus, was expressed in E. coliand purified by using conventional chromatography techniques.

Specification

• Species: Human
• Source: Human
• Tag: His
• Description: S100A3 is a memberof the S100 family of proteins containing 2 EF-hand calcium-binding motifs.S100 proteins are localized in the cytoplasm and/or nucleus of a wide rangeof cells, and involved in the regulation of a number of cellular processessuch as cell cycle progression and differentiation. S100A3 binds calcium withlow affinity and zinc with high affinity and is believed to play a role inthe calcium-dependent differentiation of cuticle cells and in the formationof hair shafts.
• Application: SDS-PAGE
• Form: Liquid. In 20mMTris-HCl buffer (pH 8.0) containing 1mM DTT, 20% glycerol, 0.2M NaCl.
• Molecular Weight: 13.9 kDa (121aa),confirmed by MALDI-TOF
• Purity: > 90% by SDS-PAGE
• Concentration: 1 mg/ml(determined by Bradford assay)
• Sequences of aminoacids: MGSSHHHHHHSSGLVPRGSH MARPLEQAVA AIVCTFQEYA GRCGDKYKLC QAELKELLQK ELATWTPTEFRECDYNKFMS VLDTNKDCEV DFVEYVRSLA CLCLYCHEYF KDCPSEPPCS Q
• Storage: Can bestored at +4°C short term (1-2 weeks). For long term storage, aliquot andstore at -20°C or -70°C. Avoid repeated freezing and thawing cycles.
• OfficialSymbol: S100A3

Gene Information

• Gene Name: S100A3 S100 calcium bindingprotein A3 [ Homo sapiens ]
• Synonyms: S100A3; S100calcium binding protein A3; S100E; protein S100-A3;S100 calcium-binding protein A3; Protein S-100E
• Gene ID: 6274
• mRNA Refseq: NM_002960
• Protein Refseq: NP_002951
• MIM: 176992
• UniProt ID: P33764
• Chromosome Location: 1q21
• Function: calcium ion binding