Recombinant Human S100B protein

• Cat.No.: S100B-34H
• Product Overview: Recombinant Human S100B was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Description: S100B also known as protein S100-B. S100B is a protein of the S100 protein family. S100 proteins comprise a multigene family of EF-hand calcium binding proteins that engage in multiple functions in response to cellular stress. S100B protein has been implicated in oligodendrocyte progenitor cell (OPC) regeneration in response to demyelinating insult. Also, S100B and other members of S100 proteins are specifically interact with PP5-TPR and inhibited the PP5-Hsp90 interaction.
• Source: E. coli
• Species: Human
• Form: Liquid. In Phosphate Buffered Saline (pH 7.4) containing 10% glycerol
• Molecular Mass: 10.7kDa (92aa)
• AA Sequence: MSELEKAMVA LIDVFHQYSG REGDKHKLKK SELKELINNE LSHFLEEIKE QEVVDKVMET LDNDGDGECD FQEFMAFVAM VTTACHEFFEHE
• Purity: >95% by SDS - PAGE
• Storage: Can be stored at +4centigrade short term (1-2 weeks). For long term storage, aliquot and store at -20Centigrade or -70Centigrade. Avoid repeated freezing and thawing cycles.
• Concentration: 1mg/ml (determined by Bradford assay)

Gene Information

• Gene Name: S100B S100 calcium binding protein B [ Homo sapiens ]
• Official Symbol: S100B
• Synonyms: S100B; protein S100-B; S100beta; NEF; S100; S100-B
• Gene ID: 6285
• mRNA Refseq: NM_006272
• Protein Refseq: NP_006263
• MIM: 176990
• UniProt ID: P04271
• Chromosome Location: 21q22.3
• Pathway: Activated TLR4 signalling, organism-specific biosystem; Advanced glycosylation endproduct receptor signaling, organism-specific biosystem; Cytosolic sensors of pathogen-associated DNA, organism-specific biosystem; DAI mediated induction of type I IFNs, organism-specific biosystem; Immune System, organism-specific biosystem; Innate Immune System, organism-specific biosystem; MyD88 cascade initiated on plasma membrane, organism-specific biosystem
• Function: RAGE receptor binding; S100 beta binding; calcium ion binding; calcium-dependent protein binding; identical protein binding; protein binding; protein homodimerization activity; protein homodimerization activity; tau protein binding; zinc ion binding