| Cat.No. : |
S1PR5-4043H |
| Product Overview : |
Human EDG8 full-length ORF ( NP_110387.1, 1 a.a. - 398 a.a.) recombinant protein with GST-tag at N-terminal. |
| Description : |
The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008] |
| Source : |
Wheat Germ |
| Species : |
Human |
| Tag : |
GST |
| Molecular Mass : |
68.2 kDa |
| AA Sequence : |
MESGLLRPAP VSEVIVLHYN YTGKLRGARY QPGAGLRADA VVCLAVCAFI VLENLAVLLV LGRHPRFHAP MFLLLGSLTL SDLLAGAAYA ANILLSGPLT LKLSPALWFA REGGVFVALT ASVLSLLAIA LERSLTMARR GPAPVSSRGR TLAMAAAAWG VSLLLGLLPA LGWNCLGRLD ACSTVLPLYA KAYVLFCVLA FVGILAAICA LYARIYCQVR ANARRLPARP GTAGTTSTRA RRKPRSLALL RTLSVVLLAF VACWGPLFLL LLLDVACPAR TCPVLLQADP FLGLAMANSL LNPIIYTLTN RDLRHALLRL VCCGRHSCGR DPSGSQQSAS AAEASGGLRR CLPPGLDGSF SGSERSSPQR DGLDTSGSTG SPGAPTAART LVSEPAAD |
| Applications : |
Enzyme-linked Immunoabsorbent Assay
Western Blot (Recombinant protein)
Antibody Production
Protein Array |
| Notes : |
Best use within three months from the date of receipt of this protein. |
| Storage : |
Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing. |
| Storage Buffer : |
50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer. |
| Quality Control Testing : |
12.5% SDS-PAGE Stained with Coomassie Blue.
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