Recombinant Human S1PR5 Protein, GST-tagged

• Cat.No.: S1PR5-4043H
• Product Overview: Human EDG8 full-length ORF ( NP_110387.1, 1 a.a. - 398 a.a.) recombinant protein with GST-tag at N-terminal.

Specification

• Description: The lysosphingolipid sphingosine 1-phosphate (S1P) regulates cell proliferation, apoptosis, motility, and neurite retraction. Its actions may be both intracellular as a second messenger and extracellular as a receptor ligand. S1P and the structurally related lysolipid mediator lysophosphatidic acid (LPA) signal cells through a set of G protein-coupled receptors known as EDG receptors. Some EDG receptors (e.g., EDG1; MIM 601974) are S1P receptors; others (e.g., EDG2; MIM 602282) are LPA receptors.[supplied by OMIM, Mar 2008]
• Source: Wheat Germ
• Species: Human
• Tag: GST
• Molecular Mass: 68.2 kDa
• AA Sequence: MESGLLRPAPVSEVIVLHYNYTGKL RGARYQPGAGLRADAVVCLAVCAFI VLENLAVLLVLGRHPRFHAPMFLLL GSLTLSDLLAGAAYAANILLSGPLT LKLSPALWFAREGGVFVALTASVLS LLAIALERSLTMARRGPAPVSSRGR TLAMAAAAWGVSLLLGLLPALGWNC LGRLDACSTVLPLYAKAYVLFCVLA FVGILAAICALYARIYCQVRANARR LPARPGTAGTTSTRARRKPRSLALL RTLSVVLLAFVACWGPLFLLLLLDV ACPARTCPVLLQADPFLGLAMANSL LNPIIYTLTNRDLRHALLRLVCCGR HSCGRDPSGSQQSASAAEASGGLRR CLPPGLDGSFSGSERSSPQRDGLDT SGSTGSPGAPTAARTLVSEPAAD
• Applications: Enzyme-linked Immunoabsorbent Assay
  Western Blot (Recombinant protein)
  Antibody Production
  Protein Array
• Notes: Best use within three months from the date of receipt of this protein.
• Storage: Store at -80 centigrade. Aliquot to avoid repeated freezing and thawing.
• Storage Buffer: 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.

Gene Information

• Gene Name: S1PR5 sphingosine-1-phosphate receptor 5 [ Homo sapiens ]
• Official Symbol: S1PR5
• Synonyms: S1PR5; sphingosine-1-phosphate receptor 5; EDG8, endothelial differentiation, sphingolipid G protein coupled receptor, 8; sphingosine 1-phosphate receptor 5; Edg 8; S1P receptor 5; S1P receptor Edg-8; sphingosine 1-phosphate receptor EDG8; sphingosine 1-phosphate receptor Edg-8; endothelial differentiation G-protein-coupled receptor 8; endothelial differentiation, sphingolipid G-protein-coupled receptor, 8; EDG8; S1P5; Edg-8; SPPR-1; SPPR-2
• Gene ID: 53637
• mRNA Refseq: NM_001166215
• Protein Refseq: NP_001159687
• MIM: 605146
• UniProt ID: Q9H228