Recombinant Human SDR16C5, His-tagged

• Cat.No.: SDR16C5-7549H
• Product Overview: Recombinant human SDR16C5 protein, fused to His-tag at N-terminus, was expressed in E.coli and purified by using conventional chromatography techniques.

Specification

• Antigen Description: Short chain dehydrogenase/reductase family 16C, member5, also known as SDR16C5, is active in both the oxidative and reductive directions. This protein oxidizes all-trans-retinol in all-trans-retinaldehyde. No activity was detected with 11-cis-retinol or 11-cis-retinaldehyde as substrates with either NAD+/NADH or NADP+/NADPH.
• Source: E. coli
• Species: Human
• Tag: His
• Form: Liquid. In 20mM Tris-HCl buffer (pH 8.0) containing 0.15M NaCl, 10% glycerol, 1mM DTT
• Molecular Mass: 28.3 kDa (261aa) confirmed by MALDI-TOF
• Protein length: 32-269aa
• AA Sequence: MGSSHHHHHH SSGLVPRGSH MGSPKPRKNV AGEIVLITGA GSGLGRLLAL QFARLGSVLV LWDINKEGNE ETCKMAREAG ATRVHAYTCD CSQKEGVYRV ADQVKKEVGD VSILINNAGI VTGKKFLDCP DELMEKSFDV NFKAHLWTYK AFLPAMIAND HGHLVCISSS AGLSGVNGLA DYCASKFAAF GFAESVFVET FVQKQKGIKT TIVCPFFIKT GMFEGCTTGC PSLLPILEPK YAVEKIVEAI LQEKMYLYMP K
• Purity: >90% as determined by SDS - PAGE
• Applications: SDS-PAGE
• Storage: Can be stored at 4°C short term (1-2 weeks). For long term storage, aliquot and store at -20°C or -70°C.Avoid repeated freezing and thawing cycles.
• Concentration: 1 mg/ml

Gene Information

• Gene Name: SDR16C5 short chain dehydrogenase/reductase family 16C, member 5 [ Homo sapiens ]
• Official Symbol: SDR16C5
• Synonyms: SDR16C5; short chain dehydrogenase/reductase family 16C, member 5; epidermal retinol dehydrogenase 2; RDH E2; RDHE2; EPHD-2; retSDR2; epidermal retinal dehydrogenase 2; retinal short chain dehydrogenase reductase; retinal short-chain dehydrogenase reductase 2; short-chain dehydrogenase/reductase family 16C member 5; RDH#2; RDH-E2; FLJ33105
• Gene ID: 195814
• mRNA Refseq: NM_138969
• Protein Refseq: NP_620419
• MIM: 608989
• UniProt ID: Q8N3Y7
• Chromosome Location: 8q12.1
• Pathway: Retinol metabolism, organism-specific biosystem; Retinol metabolism, conserved biosystem; retinoate biosynthesis I, conserved biosystem; retinoate biosynthesis I, organism-specific biosystem
• Function: nucleotide binding; oxidoreductase activity; retinol dehydrogenase activity